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Highly Conserved Protective Epitopes on Influenza B Viruses
Influenza Antibodies, Part B With its ability to reassort in animal hosts like pigs and birds, and to cause pandemics, influenza A viruses are often in the spotlight. However, a substantial portion… Expand
Benign and malignant thyroid nodules: US differentiation--multicenter retrospective study.
PURPOSE To retrospectively evaluate the diagnostic accuracy of ultrasonographic (US) criteria for the depiction of benign and malignant thyroid nodules by using tissue diagnosis as the reference… Expand
Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer
A more complete look at the HIV-1 envelope HIV-1 uses its envelope protein (Env), a large glycoprotein present on the viral surface, to enter target cells. Env forms trimers on the viral surface.… Expand
Mibefradil block of cloned T-type calcium channels.
- R. Martin, J. Lee, L. Cribbs, E. Perez-Reyes, D. Hanck
- Chemistry, Medicine
- The Journal of pharmacology and experimental…
- 1 October 2000
Mibefradil is a tetralol derivative chemically distinct from other calcium channel antagonists. It is a very effective antihypertensive agent that is thought to achieve its action via a higher… Expand
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
- L. Kong, J. Lee, +24 authors I. Wilson
- Biology, Medicine
- Nature Structural &Molecular Biology
- 26 May 2013
A substantial proportion of the broadly neutralizing antibodies (bnAbs) identified in certain HIV-infected donors recognize glycan-dependent epitopes on HIV-1 gp120. Here we elucidate how the bnAb… Expand
Radiofrequency Ablation of Benign Thyroid Nodules and Recurrent Thyroid Cancers: Consensus Statement and Recommendations
Thermal ablation using radiofrequency is a new, minimally invasive modality employed as an alternative to surgery in patients with benign thyroid nodules and recurrent thyroid cancers. The Task Force… Expand
Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers.
Broadly neutralizing HIV antibodies are much sought after (a) to guide vaccine design, both as templates and as indicators of the authenticity of vaccine candidates, (b) to assist in structural… Expand
Ultrasonography Diagnosis and Imaging-Based Management of Thyroid Nodules: Revised Korean Society of Thyroid Radiology Consensus Statement and Recommendations
The rate of detection of thyroid nodules and carcinomas has increased with the widespread use of ultrasonography (US), which is the mainstay for the detection and risk stratification of thyroid… Expand
Prognostic Biomarkers for Esophageal Adenocarcinoma Identified by Analysis of Tumor Transcriptome
Background Despite many attempts to establish pre-treatment prognostic markers to understand the clinical biology of esophageal adenocarcinoma (EAC), validated clinical biomarkers or parameters… Expand
Ultrasonography and the Ultrasound-Based Management of Thyroid Nodules: Consensus Statement and Recommendations
The detection of thyroid nodules has become more common with the widespread use of ultrasonography (US). US is the mainstay for detecting and making the differential diagnosis of thyroid nodules as… Expand