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- Publications
- Influence
Influence of CYP2D6 activity on the disposition and cardiovascular toxicity of the antidepressant agent venlafaxine in humans.
- E. Lessard, M. Yessine, B. Hamelin, G. O'Hara, J. Leblanc, J. Turgeon
- Biology, Medicine
- Pharmacogenetics
- 1 August 1999
According to in-vitro studies with microsomes from human livers and from yeast expression systems with high CYP2D6 activity, the major oxidation pathway of venlafaxine is catalysed by CYP2D6. In this… Expand
Surgical management and radiological characteristics of bronchogenic cysts.
- H. Suen, D. Mathisen, +4 authors A. Hilgenberg
- Medicine
- The Annals of thoracic surgery
- 1 February 1993
Forty-two patients with bronchogenic cysts were treated over a 30-year period (1962 to 1991). The location was mediastinal in 37 and intrapulmonary in 5. Cysts were symptomatic in 21 patients (50%)… Expand
Mechanism of enhanced lipolysis in adipose tissue of exercise-trained rats.
- L. Bukowiecki, J. Lupien, N. Folléa, A. Paradis, D. Richard, J. Leblanc
- Biology, Medicine
- The American journal of physiology
- 1 December 1980
The effects of exercise training and food restriction on the regulation of lipolysis were studied comparatively in adipocytes isolated from male and female rats. Exercise training inhibited cell… Expand
Diphenhydramine Alters the Disposition of Venlafaxine Through Inhibition of CYP2D6 Activity in Humans
- E. Lessard, M. Yessine, +5 authors J. Turgeon
- Medicine, Chemistry
- Journal of clinical psychopharmacology
- 1 April 2001
CYP2D6 is the major enzyme involved in the metabolism of venlafaxine. Subjects with a low CYP2D6 activity have increased plasma concentrations of venlafaxine that may predispose them to… Expand
Transaxillary pleurectomy for treatment of spontaneous pneumothorax.
- J. Deslauriers, M. Beaulieu, J. P. Després, M. Lemieux, J. Leblanc, M. Desmeules
- Medicine
- The Annals of thoracic surgery
- 1 December 1980
In the 16-year period 1962 to 1978, 409 transaxillary apical pleurectomies were carried out for definitive treatment of spontaneous pneumothorax in 362 patients. Surgical indications included… Expand
Role of palatability on meal-induced thermogenesis in human subjects.
- J. Leblanc, L. Brondel
- Biology, Medicine
- The American journal of physiology
- 1 March 1985
To study the possible participation of food-induced sensory stimulation on meal thermogenesis an experiment was performed with eight female subjects. On alternate days subjects were fed either a… Expand
Effects of age, sex, and physical fitness on responses to local cooling.
- J. Leblanc, J. Côté, S. Dulac, F. Dulong-Turcot
- Chemistry, Medicine
- Journal of applied physiology: respiratory…
- 1 May 1978
The response to local cooling was estimated by the cold hand test (5 degrees C for 2 min) and the cold face test (0 degrees C with 66 km.h-1 wind for 2 min). Heart rate, blood pressure, and skin… Expand
Tolerance of Gaspe fishermen to cold water.
- J. Leblanc, J. Hildes, O. Héroux
- Chemistry, Medicine
- Journal of applied physiology
- 1 November 1960
A group of Gaspe fishermen used to cold water immersion and control subjects from the same vicinity were studied to determine if the fishermen's hands were adapted to cold. With one hand immersed i...
Ipsilateral acoustic reflex stimulation in normal and sensorineural impaired ears: a preliminary report.
- Thomas J. Fria, J. Leblanc, R. Kristensen, P. Alberti
- Medicine
- Canadian journal of otolaryngology
- 1975
Ipsilateral acoustic reflex thresholds were measured at 1,000 Hz and 2,000 Hz in 38 subjects with normal hearing and in 107 subjects with a symmetrical sensorineural hearing loss. Acoustic reflex… Expand