• Publications
  • Influence
Microbial culturomics: paradigm shift in the human gut microbiome study.
TLDR
Culturomics complements metagenomics by overcoming the depth bias inherent in metagenomic approaches, and identifies 174 species never described previously in the human gut.
Culture of previously uncultured members of the human gut microbiota by culturomics
TLDR
It is shown that the use of culturomics allows the culture of organisms corresponding to sequences previously not assigned, which doubles the number of species isolated at least once from the human gut.
Systemic Tropheryma whipplei: Clinical Presentation of 142 Patients With Infections Diagnosed or Confirmed in a Reference Center
TLDR
In the 113 patients with classic WD, the main symptom was arthralgia, which explains the many cases misdiagnosed as inflammatory rheumatoid disease, and developed new tools in the center in Marseille, France, to optimize the diagnosis of T whipplei infections.
A polyphasic strategy incorporating genomic data for the taxonomic description of novel bacterial species.
TLDR
The pros and cons of genome sequencing for taxonomy are reviewed and it is proposed that the incorporation of genome sequences in taxonomic studies has the advantage of using reliable and reproducible data.
Culturing the human microbiota and culturomics
TLDR
How culturomics has extended the understanding of bacterial diversity, and how it can be applied to the study of the human microbiota and the potential implications for human health are described.
Hydroxychloroquine and Azithromycin as a treatment of COVID-19: preliminary results of an open-label non-randomized clinical trial
TLDR
Hydxychloroquine is significantly associated with viral load reduction/disappearance in patients with COVID-19 and its effect is reinforced by Azithromycin.
...
...