J. Ladau

Publications48
h-index20
Citations3,778
Highly Influential Citations142
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A communal catalogue reveals Earth’s multiscale microbial diversity
TLDR
A meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project is presented, creating both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earth’s microbial diversity.
American Gut: an Open Platform for Citizen Science Microbiome Research
TLDR
The utility of the living data resource and cross-cohort comparison is demonstrated to confirm existing associations between the microbiome and psychiatric illness and to reveal the extent of microbiome change within one individual during surgery, providing a paradigm for open microbiome research and education.
Continental-scale distributions of dust-associated bacteria and fungi
TLDR
It is found that airborne microbial communities, such as terrestrial plants and animals, exhibit nonrandom geographic patterns, and the factors that shape the continental-scale distributions of microbial taxa are identified, and this first atlas of airborne bacterial and fungal distributions across the continental United States is generated.
Marked seasonal variation in the wild mouse gut microbiota
TLDR
It is suggested that environmental factors have a major role in shaping temporal variations in microbial community structure within natural populations.
Global marine bacterial diversity peaks at high latitudes in winter
TLDR
These maps provide the first picture of bacterial distributions at a global scale and suggest important differences between the diversity patterns of bacteria compared with other organisms.
Reconstructing the Microbial Diversity and Function of Pre-Agricultural Tallgrass Prairie Soils in the United States
TLDR
The soil microbial diversity that once existed in this biome was reconstructed by analyzing relict prairie soils and found that the biogeographical patterns were largely driven by changes in the relative abundance of Verrucomicrobia, a poorly studied bacterial phylum that appears to dominate many prairies.
Phylogenetically Novel Uncultured Microbial Cells Dominate Earth Microbiomes
TLDR
It is shown that uncultured microbes, often from deeply phylogenetically divergent groups, dominate nonhuman environments on Earth, and their undiscovered physiologies may matter for Earth systems.
Urban greenness influences airborne bacterial community composition.
PhylOTU: A High-Throughput Procedure Quantifies Microbial Community Diversity and Resolves Novel Taxa from Metagenomic Data
TLDR
Comparisons of PCR and shotgun sequenced SSU-rRNA markers derived from the global open ocean revealed that while PCR libraries identify more OTUs per sequenced residue, metagenomic libraries recover a greater taxonomic diversity of OTUs.
A genomic catalog of Earth’s microbiomes
TLDR
The utility of this collection of >10,000 metagenomes collected from diverse habitats covering all of Earth’s continents and oceans is demonstrated for understanding secondary-metabolite biosynthetic potential and for resolving thousands of new host linkages to uncultivated viruses.
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