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Collagen type I mRNA levels in cultured human lamina cribrosa cells: effects of elevated hydrostatic pressure.
In primary open-angle glaucoma, elevated intraocular pressure is associated with distortion and reorganization of the connective tissue plates of the lamina cribrosa. We have previously postulatedExpand
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Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with acute leukemia.
The pharmacokinetics of high-dose cytosine arabinoside (HiDAC) given as a three-hour intravenous infusion at 3 g/m2 were studied in five patients with acute leukemia during relapse and/or remissionExpand
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Effect of uracil arabinoside on metabolism and cytotoxicity of cytosine arabinoside in L5178Y murine leukemia.
Pretreatment of L5178Y murine leukemia cells with uracil arabinoside (ara-U) enhances the cytotoxicity of cytosine arabinoside (ara-C). This effect is mediated by the cytostatic effect of ara-U,Expand
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[Inhibitory effect of hydroxycamptothecin on colony formation of KB cells and DNA damage].
Hydroxycamptothecin (HCPT) is an antitumor alkaloid isolated from Camptotheca acuminata Decaisne, a tree native to China. The present investigation showed that HCPT possesses strong cytotoxicity onExpand
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[Distribution and excretion of 10-hydroxycamptothecin and its influence on immune response (author's transl)].
  • J. L. Yang, J. Han, B. Xu
  • Biology, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica…
  • 1 September 1980
3H-hydroxycamptothecin was injected into the tail vein of mice in a dose of 10 mg/kg. The decline of radioactivity in the blood showed a biphasic curve. The first biological half-life(t1/2alpha) wasExpand
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[Cultured human hepatoma cells (BEL-7404) for anticancer drugs screening].
A quantitative method of tumor cell culture for evaluating anticancer agents in viro was established. Typical cell-growth curve was seen when human hepatoma( BEL-7404) 2.5*10(2)-2.5*10(4) cell/wellExpand
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[Cytotoxicity of hydroxycamptothecin and four other antineoplastic agents on KB cells].
The cytotoxicity of l0-hydroxycamptothecip (HCPT), homoharringtonine (HHAR), lycobetaine (LBT), 5-fluorouracil (5-FU), and vincristine (VCR) on KB cell was studied by means of colony formation methodExpand
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[Effect on animal tumors and toxicity of lycobetaine acetate (author's transl)].
Lycobetaine, a derivative of lycorine, is a new type of antitumor drug. When lycobetaine acetate (AT-1840) was given ip to mice and rats inoculated with Ehrlich ascites carcinoma, ascites hepatoma,Expand
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Path tracking laws and implementation of a vision-based wheeled mobile robot
This paper has studied techniques for building system configuration, control architecture and implementation of a vision-based wheeled mobile robot. The completed WMR has been built with theExpand
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