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Sesquiterpene benzoxazoles and sesquiterpene quinones from the marine sponge Dactylospongia elegans.
All compounds isolated from the methanol extract of the marine sponge Dactylospongia elegans were found to have activities in the range 1.8-46 μM and lacked selectivity for tumor versus normal cell lines.
Detailed NMR, Including 1,1-ADEQUATE, and Anticancer Studies of Compounds from the Echinoderm Colobometra perspinosa
A thorough NMR investigation of rhodoptilometrin was undertaken, finding the in vitro anticancer activity of the original extract was found to be associated with 1, 3 and 5.
Metachromins U-W: cytotoxic merosesquiterpenoids from an Australian specimen of the sponge Thorecta reticulata.
Three new merosesquiterpenoids, metachromins U, V, and W (1-3), were isolated from a specimen of the marine sponge Thorecta reticulata collected off Hunter Island, Tasmania, Australia. Structures of
A New Diketopiperazine, Cyclo-(4-S-hydroxy-R-proline-R-isoleucine), from an Australian Specimen of the Sponge Stelletta sp. †
The isolation and structure elucidation of the diketopiperazine, together with the activity of 1–8 against a panel of human and mammalian cell lines are discussed.
Comosusols A-D and comosone A: cytotoxic compounds from the brown alga Sporochnus comosus.
Bioassay-guided fractionation of extracts of the brown alga Sporochnus comosus led to the isolation of five new compounds, comosUSols A-D (3-6) and comosone A (7), which were elucidated using standard one- and two-dimensional NMR techniques, as well as comparison with literature values.
A Great Barrier Reef Sinularia sp. Yields Two New Cytotoxic Diterpenes
The methanol extract of a Sinularia sp., collected from Bowden Reef, Queensland, Australia, yielded ten natural products. These included the new nitrogenous diterpene
Update of Spectroscopic Data for 4-Hydroxydictyolactone and Dictyol E Isolated from a Halimeda stuposa — Dictyota sp. Assemblage †
The methanol extract of an assemblage of Halimeda stuposa and a Dictyota sp., yielded three natural products characteristic of Dictyota sp., and one of Halimeda sp. These included the xenicane