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Neuron-like Differentiation of Adipose-Derived Stem Cells From Infant Piglets in Vitro
Abstract Background/Objective: Adipose-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that can be extracted from adipose tissue and obtained by a less invasive method and in largerExpand
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Delayed Hemorrhagic Hypotension Exacerbates the Hemodynamic and Histopathologic Consequences of Traumatic Brain Injury in Rats
Alterations in cerebral autoregulation and cerebrovascular reactivity after traumatic brain injury (TBI) may increase the susceptibility of the brain to secondary insults, including arterialExpand
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Selective brain cooling increases cortical cerebral blood flow in rats.
To evaluate the effect of selective brain cooling on cortical cerebral blood flow, we reduced brain temperature in nitrous oxide anesthetized adult rats using a high speed fan while keeping rectalExpand
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Pediatric Spinal Cord Injury in Infant Piglets: Description of a New Large Animal Model and Review of the Literature
Abstract Objective: To develop a new, clinically relevant large animal model of pediatric spinal cord injury (SCI) and compare the clinical and experimental features of pediatric SCI. Methods: InfantExpand
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Endothelium‐Derived Nitric Oxide Synthase Inhibition: Effects on Cerebral Blood Flow, Pial Artery Diameter, and Vascular Morphology in Rats
Background and Purpose We determined the effects of inhibiting the production of cerebral endothelium- derived nitric oxide on pial artery diameter, cortical blood flow, and vascular morphology.Expand
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Fructose‐1,6‐Bisphosphate Reduces Infarct Volume After Reversible Middle Cerebral Artery Occlusion in Rats
Background and Purpose We tested the hypothesis that fructose-1,6-bisphosphate, when administered 10 minutes before the end of 2 hours of reversible middle cerebral artery occlusion, reducesExpand
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Traumatic injury activates MAP kinases in astrocytes: mechanisms of hypothermia and hyperthermia.
Hyperthermia is common following traumatic brain injury (TBI) and has been associated with poor neurologic outcome, and hypothermia has emerged as a potentially effective therapy for TBI, althoughExpand
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Snoezelen: A controlled multi-sensory stimulation therapy for children recovering from severe brain injury
Objective: To investigate the effects of Snoezelen therapy on physiological, cognitive and behavioural changes in children recovering from severe traumatic brain injury (TBI). Methods: AnExpand
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New Pediatric Model of Ischemic Stroke in Infant Piglets by Photothrombosis: Acute Changes in Cerebral Blood Flow, Microvasculature, and Early Histopathology
Background and Purpose— The etiology and pathophysiology of acute ischemic stroke in children differ greatly from those in adults. The purpose of this study was to establish a new pediatric model ofExpand
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The Effect of Nitric Oxide Synthase Inhibition on Infarct Volume After Reversible Focal Cerebral Ischemia in Conscious Rats
Background and Purpose Previous in vitro and in vivo studies of the effects of nitric oxide synthase inhibition in the central nervous system have yielded conflicting results concerning the role ofExpand
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