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Early use of TIPS in patients with cirrhosis and variceal bleeding
This study clearly shows that in this high-risk cirrhotic population, mortality is reduced with early use of TIPS and the use of vasoactive drugs followed by endoscopic therapy, nonselective β-blockers, and nitrates cannot be considered a limitation of the study. Expand
Endoscopic sclerotherapy as compared with endoscopic ligation for bleeding esophageal varices.
- G. Stiegmann, J. Goff, +6 authors S. Lowenstein
- The New England journal of medicine
- 1 December 1992
Patients with cirrhosis who have bleeding esophageal varices have fewer treatment-related complications and better survival rates when they are treated by esphageal ligation than when they were treated by sclerotherapy. Expand
Subclinical hepatic encephalopathy: proton MR spectroscopic abnormalities.
H-1 MR spectroscopy allows accurate diagnosis of SCHE, and the results suggest an important role for myo-inositol in psychomotor and visuopractic functions. Expand
Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage.
- J. Korula
- 1 August 1991
Fulminant reactivation of hepatitis B due to envelope protein mutant that escaped detection by monoclonal HBsAg ELISA
- W. Carman, J. Korula, L. Wallace, R. Macphee, L. Mimms, R. Decker
- Medicine, Biology
- The Lancet
- 3 June 1995
PCR sequencing revealed a substitution of arginine for glycine at position 145 of HBsAg in the major neutralising epitope cluster, the a determinant, as well as a 2-aminoacid insertion of asparagine and threonine between positions 122 and 123, immediately upstream of this determinant. Expand
Acute esophageal variceal sclerotherapy. Results of a prospective randomized controlled trial.
Although there was no difference in survival between the two groups, it is concluded that sclerotherapy is better than conventional treatment in the acute management of variceal bleeding. Expand
A prospective, randomized controlled trial of chronic esophageal variceal sclerotherapy
Esophageal variceal sclerotherapy decreased rebleeding as evidenced by a decrease in the mean bleeding risk factor, transfusion requirement and by an increase in bleeding free interval; differences between the treated and control groups in these parameters were especially significant after variceAL obliteration. Expand
Diagnostic features of tuberculous peritonitis in the absence and presence of chronic liver disease: a case control study.
- A. Shakil, J. Korula, G. Kanel, N. Murray, T. Reynolds
- The American journal of medicine
- 1 February 1996
In patients with suspected TBP, ascitic fluid protein of > 25 g/L, SAAG of < 11 g/ L and LDH of > 90 U/L have high sensitivity for the disease. Expand
Endoscopic sclerotherapy as compared with endoscopic ligation for bleeding esophagal varices
This randomized trial compared endoscopic sclerotherapy and endoscopic ligation in 129 patients with cirrhosis who had proved bleeding from esophageal varices and determined the incidence of complications and recurrences of bleeding, the number of treatments needed to eradicate varices, and survival. Expand
A simple and inexpensive method of removal or replacement of gastrostomy tubes.
This simple method is safe, inexpensive, can be offered to the large majority of patients with percutaneous endoscopic gastrostomy tubes, and avoids the need for endoscopic removal. Expand