• Publications
  • Influence
A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease.
TLDR
An expert panel to review and develop standard terminologies and definitions related to wasting, cachexia, malnutrition, and inflammation in CKD and AKI recommends the term 'protein-energy wasting' for loss of body protein mass and fuel reserves.
A malnutrition-inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients.
TLDR
The MIS appears to be a comprehensive scoring system with significant associations with prospective hospitalization and mortality, as well as measures of nutrition, inflammation, and anemia in MHD patients, and may be superior to the conventional SGA and the DMS as a predictor of dialysis outcome and an indicator of MICS.
Malnutrition-inflammation complex syndrome in dialysis patients: causes and consequences.
TLDR
Because MICS leads to a low body mass index, hypocholesterolemia, hypocreatininemia, and hypohomocysteinemia, a "reverse epidemiology" of cardiovascular risks can occur in dialysis patients, obesity, hypercholesterolesmia, and increased blood levels of creatinine and homocysteine appear to be protective and paradoxically associated with a better outcome.
Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients.
TLDR
Associations between high serum parathyroid hormone and increased death risk were masked by case-mix characteristics of MHD patients, and Administration of any dose of paricalcitol was associated with improved survival in time-varying models.
National kidney foundation K/DOQI clinical practice guidelines for nutrition in chronic renal failure.
  • J. Kopple
  • Medicine
    American journal of kidney diseases : the…
  • 2001
TLDR
A number of the more prominent clinical practice guidelines for the adults are discussed, including the recommendation that the protein-energy nutritional status in patients with advanced chronic renal failure should be assessed by a panel of measures rather than by any single measure.
Association among SF36 quality of life measures and nutrition, hospitalization, and mortality in hemodialysis.
TLDR
In patients on MHD the SF36 appears to have significant associations with measures of nutritional status, anemia, and clinical outcomes, including prospective hospitalization and mortality, even though obesity, unlike undernutrition, is not generally an indicator of poor outcome in MHD.
Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients.
TLDR
An inverse association between conventional risk factors and clinical outcome in dialysis patients is found and it is possible that new standards or goals for such traditional risk factors as body mass, serum cholesterol, and blood pressure should be considered for these individuals.
Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: a randomized controlled trial.
TLDR
Ramipril, compared with amlodipine, retards renal disease progression in patients with hypertensive renal disease and proteinuria and may offer benefit to patients without proteinuria.
Kinetic analysis of lead metabolism in healthy humans.
TLDR
The steady state kinetics of lead metabolism were studied in five healthy men with stable isotope tracers and the data suggest a three compartmental model for lead metabolism.
The End-Stage Renal Disease Adherence Questionnaire (ESRD-AQ): testing the psychometric properties in patients receiving in-center hemodialysis.
TLDR
The methodological approach used to develop and test the psychometric properties of the ESRD-Adherence Questionnaire (ESRD-AQ) in a cohort of patients receiving maintenance HD at dialysis centers in Los Angeles County supports that the instrument is reliable and valid and is easy to administer.
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