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High expression of ezrin predicts poor prognosis in uterine cervical cancer
BackgroundEzrin, a member of the ezrin/radixin/moesin (ERM) protein family, plays a pivotal role in tumor invasion and metastasis. This study is aimed to investigate the clinicopathologicalExpand
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Ezrin contributes to cervical cancer progression through induction of epithelial-mesenchymal transition
Cervical cancer is the third most common cancer in females worldwide. The treatment options for advanced cervical cancer are limited, leading to high mortality. Ezrin is aExpand
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EGF induces epithelial-mesenchymal transition through phospho-Smad2/3-Snail signaling pathway in breast cancer cells
Epithelial-mesenchymal transition (EMT) can contribute to tumor invasion, metastasis, and resistance to chemotherapy or hormone therapy. EMT may be induced by a variety of growth factors, such asExpand
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DEK overexpression is correlated with the clinical features of breast cancer.
To investigate the clinicopathological significance of DEK overexpression in breast cancers, a total of 196 cases, including 20 of normal tissues, 12 of intraductal hyperplasia, 31 of ductalExpand
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Mechanisms Underlying Cancer Growth and Apoptosis by DEK Overexpression in Colorectal Cancer
Our previous study indicated that DEK protein was overexpressed in colorectal carcinoma (CRC) compared with the normal colorectal mucosa. DEK was also significantly correlated with the prognosticExpand
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Sineoculis homeobox homolog 1 protein is associated with breast cancer progression and survival outcome.
Sineoculis homeobox homolog 1 (SIX1) is one of the transcription factors that act as master regulators of development and is frequently dysregulated in cancer. This study explores the roles of SIX1Expand
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NQO1 overexpression is associated with poor prognosis in squamous cell carcinoma of the uterine cervix
BackgroundNQO1 (NAD(P)H: quinone oxidoreductase-1), located on chromosome 16q22, functions primarily to protect normal cells from oxidant stress and electrophilic attack. Recent studies have revealedExpand
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Overexpression of sineoculis homeobox homolog 1 predicts poor prognosis of hepatocellular carcinoma.
High expression levels of the human sineoculis homeobox homolog 1 (SIX1) gene have been correlated with numerous human malignancies. The SIX1 protein is involved in chromatin reconstruction and geneExpand
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Primary mucinous cystadenocarcinoma of the breast coexisting with invasive ductal carcinoma : a case report and review of the literature
Mucinous cystadenocarcinoma (MCA) is an extremely rare variant of primary breast carcinoma that bears a striking resemblance to MCAs of the ovary and pancreas. A 58-year-old woman underwentExpand
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Ezrin promotes breast cancer progression by modulating AKT signals
BackgroundEzrin, which is known as a cytoskeleton linker protein, is closely linked with the metastatic progression of cancer and is frequently abnormally expressed in aggressive cancer types.Expand
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