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The predictive value of exhaled nitric oxide measurements in assessing changes in asthma control.
Exhaled nitric oxide (eNO) levels are increased in untreated or unstable asthma and measurements can be made easily. Our aim was to assess the usefulness of eNO for diagnosing and predicting loss ofExpand
A Randomized Trial of Modafinil for the Treatment of Fatigue and Excessive Daytime Sleepiness in Individuals with Chronic Traumatic Brain Injury
BackgroundThis study examines the efficacy of modafinil in treating fatigue and excessive daytime sleepiness in individuals with traumatic brain injury (TBI). MethodsA single-center, double-blind,Expand
Effects of testosterone and progressive resistance exercise in healthy, highly functioning older men with low-normal testosterone levels.
CONTEXT Aging in men is associated with reduced testosterone (T) levels and physiological changes leading to frailty, but the benefits of T supplementation are inconclusive. OBJECTIVE We studiedExpand
Predicting Functional Performance and Range of Motion Outcomes After Total Knee Arthroplasty
ObjectiveThe aim of this study was to assess the predictive value of functional performance and range of motion measures on outcomes after total knee arthroplasty. DesignThis is a secondary analysisExpand
Remote Source Document Verification in Two National Clinical Trials Networks: A Pilot Study
Objective Barriers to executing large-scale randomized controlled trials include costs, complexity, and regulatory requirements. We hypothesized that source document verification (SDV) via remoteExpand
Phenotypic relationships of prostatic intraepithelial neoplasia to invasive prostatic carcinoma.
Thirty-one snap-frozen human prostate specimens containing examples of benign hyperplasia, prostatic intraepithelial neoplasia (PIN), and invasive carcinoma were analyzed using a panel of 24Expand
Rivaroxaban in Peripheral Artery Disease after Revascularization.
BACKGROUND Patients with peripheral artery disease who have undergone lower-extremity revascularization are at high risk for major adverse limb and cardiovascular events. The efficacy and safety ofExpand
Effects of dehydroepiandrosterone replacement therapy on bone mineral density in older adults: a randomized, controlled trial.
CONTEXT Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) decrease with aging and are important androgen and estrogen precursors in older adults. Declines in DHEAS with aging may contribute toExpand
Association of Lipoprotein(a) With Risk of Recurrent Ischemic Events Following Acute Coronary Syndrome: Analysis of the dal-Outcomes Randomized Clinical Trial
Importance It is uncertain whether lipoprotein(a) [Lp(a)], which is associated with incident cardiovascular disease, is an independent risk factor for recurrent cardiovascular events after acuteExpand
Timing of ibuprofen use and musculoskeletal adaptations to exercise training in older adults
Prostaglandins (PGs) increase in bone in response to mechanical loading and stimulate bone formation. Inhibition of cyclooxygenase (COX), the enzyme responsible for PG synthesis, by non-steroidalExpand