Author pages are created from data sourced from our academic publisher partnerships and public sources.
Share This Author
Differential diagnosis of suspected multiple sclerosis: a consensus approach
Background and objectives Diagnosis of multiple sclerosis (MS) requires exclusion of diseases that could better explain the clinical and paraclinical findings. A systematic process for exclusion of…
Multiple sclerosis in the Japanese population
- J. Kira
- Biology, MedicineThe Lancet Neurology
- 1 February 2003
A nationwide survey of hypertrophic pachymeningitis in Japan
- T. Yonekawa, H. Murai, J. Kira
- MedicineJournal of Neurology, Neurosurgery & Psychiatry
- 22 November 2013
Antineutrophil cytoplasmic antibody (ANCA)-related HP is the most frequent form, followed by IgG4/MFS-related HP, which have unique features, which may help to differentiate background causes.
Western versus asian types of multiple sclerosis: Immunogenetically and clinically distinct disorders
Heterogeneity inthe immunogenetic background and in the magnetic resonance imaging features between the two subtypes of MS suggests the presence of two etiologically distinct diseases in Asians.
Anti-neurofascin antibody in patients with combined central and peripheral demyelination
In anti-neurofascin antibody–positive CCPD patients, including those with a limited response to corticosteroids, IV immunoglobulin or plasma exchange alleviated the symptoms, recognition of this antibody may be important, because patients with CCPD who are antibody positive respond well to IV immunglobulinor plasma exchange.
Demyelinating and axonal features of Charcot-Marie-Tooth disease with mutations of myelin-related proteins (PMP22, MPZ and Cx32): a clinicopathological study of 205 Japanese patients.
Three major myelin-related protein mutations induced varied degrees of axonal and demyelinating phenotypic features according to the specific gene mutation as well as the stage of disease advancement, while clinically evident muscle wasting was attributable to loss of functioning large axons.
HLA-DPB1*0501-associated opticospinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies.
- K. Yamasaki, I. Horiuchi, J. Kira
- Medicine, PsychologyBrain : a journal of neurology
- 1 September 1999
The marked differences in the clinical and MRI findings as well as in the immunogenetic backgrounds between the opticospinal multiple sclerosis and Western-type multiple sclerosis together suggest that HLA-DPB1*0501-associated opticospinals multiple sclerosis is a distinct subtype of multiple sclerosis.
Temporal changes and geographical differences in multiple sclerosis phenotypes in Japanese: nationwide survey results over 30 years
Findings suggest that MS phenotypes are drastically altered by environmental factors, such as latitude and “Westernization,” as well as in Japan.
Heterozygous deletion of ITPR1, but not SUMF1, in spinocerebellar ataxia type 16
The data provide evidence that haploinsufficiency of ITPR1 alone causes SCA16 and SCA15 and the copy number of these genes by real time quantitative polymerase chain reaction (PCR) is determined and found a heterozygous deletion of exons 1-48 of IT PR1, but not SUMF1 in SCA 16.
Characteristic Cerebrospinal Fluid Cytokine/Chemokine Profiles in Neuromyelitis Optica, Relapsing Remitting or Primary Progressive Multiple Sclerosis
In NMO, over-expression of a cluster of Th17- and Th1-related proinflammatory cytokines/chemokines is characteristic, while in PPMS, increased CCL4 and CXCL10 levels may reflect on-going low grade T cell and macrophage/microglia inflammation in the central nervous system.