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A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders.
Nuclear factor-erythroid 2-related factor-2 (Nrf2) is a key transcription factor that plays a central role in cellular defense against oxidative and electrophilic insults by timely induction of… Expand
Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1
ABSTRACT HuR influences gene expression programs and hence cellular phenotypes by binding to hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular RNAs (circRNAs) and… Expand
Microbial community and metabolomic comparison of irritable bowel syndrome faeces
- K. Ponnusamy, Jung Nam Choi, J. Kim, Sun-Young Lee, C. Lee
- Biology, Medicine
- Journal of medical microbiology
- 1 June 2011
Human health relies on the composition of microbiota in an individual’s gut and the synthesized metabolites that may alter the gut environment. Gut microbiota and faecal metabolites are involved in… Expand
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
- J. Kim, R. Villadsen, +12 authors O. Petersen
- Medicine, Biology
- Proceedings of the National Academy of Sciences
- 27 March 2012
The majority of human breast cancers exhibit luminal epithelial differentiation. However, most aggressive behavior, including invasion and purported cancer stem cell activity, are considered… Expand
Metabolomics analysis reveals the compositional differences of shade grown tea (Camellia sinensis L.).
- K. Ku, Jung Nam Choi, +5 authors C. Lee
- Chemistry, Medicine
- Journal of agricultural and food chemistry
- 13 January 2010
The different cultivation methods affect tea quality by altering the basic metabolite profiles. In this study, the metabolome changes were investigated in green tea and shade cultured green tea… Expand
7SL RNA represses p53 translation by competing with HuR
- Kotb Abdelmohsen, A. Panda, +9 authors M. Gorospe
- Biology, Medicine
- Nucleic acids research
- 14 August 2014
Noncoding RNAs (ncRNAs) and RNA-binding proteins are potent post-transcriptional regulators of gene expression. The ncRNA 7SL is upregulated in cancer cells, but its impact upon the phenotype of… Expand
Clinicopathologic Risk Factors for the Local Recurrence of Phyllodes Tumors of the Breast
- Jae Hyuck Jang, Min-young Choi, +11 authors Jung-Hyun Yang
- Annals of Surgical Oncology
- 4 April 2012
BackgroundPhyllodes tumors (PTs) are rare breast tumors that usually occur in middle-aged women. Here we discuss our recent experiences in the diagnosis, surgical management, and clinical follow-up… Expand
Ex vivo characteristics of human amniotic membrane-derived stem cells.
Cells were isolated from four human amniotic membranes, and their biological characteristics analyzed during ex vivo expansion. Morphologically homogenous populations of fibroblast-like cells were… Expand
From e-government to social government: Twitter use by Korea's central government
This study investigates the nature of social media interactions and networking strategies in the Korean government by extracting tweets, follower/following relationships, and hyperlinks for 32 ministries. Expand
Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression.
Mitogen-activated protein kinases (MAPKs) are thought to have a critical role in lipopolysaccharide (LPS)-induced immune responses but the molecular mechanisms underlying the mediation of these… Expand