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A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders.
Nuclear factor-erythroid 2-related factor-2 (Nrf2) is a key transcription factor that plays a central role in cellular defense against oxidative and electrophilic insults by timely induction ofExpand
Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1
ABSTRACT HuR influences gene expression programs and hence cellular phenotypes by binding to hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular RNAs (circRNAs) andExpand
Microbial community and metabolomic comparison of irritable bowel syndrome faeces
Human health relies on the composition of microbiota in an individual’s gut and the synthesized metabolites that may alter the gut environment. Gut microbiota and faecal metabolites are involved inExpand
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
The majority of human breast cancers exhibit luminal epithelial differentiation. However, most aggressive behavior, including invasion and purported cancer stem cell activity, are consideredExpand
Metabolomics analysis reveals the compositional differences of shade grown tea (Camellia sinensis L.).
The different cultivation methods affect tea quality by altering the basic metabolite profiles. In this study, the metabolome changes were investigated in green tea and shade cultured green teaExpand
7SL RNA represses p53 translation by competing with HuR
Noncoding RNAs (ncRNAs) and RNA-binding proteins are potent post-transcriptional regulators of gene expression. The ncRNA 7SL is upregulated in cancer cells, but its impact upon the phenotype ofExpand
Clinicopathologic Risk Factors for the Local Recurrence of Phyllodes Tumors of the Breast
BackgroundPhyllodes tumors (PTs) are rare breast tumors that usually occur in middle-aged women. Here we discuss our recent experiences in the diagnosis, surgical management, and clinical follow-upExpand
Ex vivo characteristics of human amniotic membrane-derived stem cells.
Cells were isolated from four human amniotic membranes, and their biological characteristics analyzed during ex vivo expansion. Morphologically homogenous populations of fibroblast-like cells wereExpand
From e-government to social government: Twitter use by Korea's central government
This study investigates the nature of social media interactions and networking strategies in the Korean government by extracting tweets, follower/following relationships, and hyperlinks for 32 ministries. Expand
Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expression.
Mitogen-activated protein kinases (MAPKs) are thought to have a critical role in lipopolysaccharide (LPS)-induced immune responses but the molecular mechanisms underlying the mediation of theseExpand