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Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology.
VEGF released by glioma cells in situ most likely accounts for pathognomonic histopathologic and clinical features of GBM tumors in patients, including striking tumor angiogenesis, increased cerebral edema and hypercoagulability manifesting as focal tumor necrosis, deep vein thrombosis, or pulmonary embolism. Expand
Association of aldehyde dehydrogenase 1 expression and biologically aggressive features in breast cancer.
Findings suggest that ALDH1 expression in tumor tissue is associated with a biologically aggressive phenotype. Expand
Ultraviolet irradiation induces BRCA2 protein depletion through a p53-independent and protein synthesis-dependent pathway.
It is demonstrated that BRCA2 is involved in a DNA-damaging signaling pathway induced by UV radiation and that expression of B RCA2 can protect cells from UV-mediated cell death. Expand
Time-Resolved Measurements of PM2.5 Carbonaceous Aerosols at Gosan, Korea
  • T. Batmunkh, Y. Kim, +8 authors J. An
  • Chemistry, Medicine
  • Journal of the Air & Waste Management Association
  • 31 October 2011
A better understanding of the chemical characteristics of carbonaceous aerosol influenced by increasing anthropogenic pollution in the downwind regions of the East Asian continent is needed in order to determine their impacts on regional air quality and climate change. Expand
Antiangiogenesis treatment for gliomas: transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo.
This is the first time that an adenoviral vector is used to transfer antisense VEGF sequence into glioma cells in an animal model, and results suggest that this system may have clinical and therapeutic utility. Expand
Three terminal magnetic tunnel junction utilizing the spin Hall effect of iridium-doped copper
We show a three terminal magnetic tunnel junction (MTJ) with a 10-nm thick channel based on an interconnection material Cu with 10% Ir doping. By applying a current density of less than 1012 A m−2 toExpand
Clinical signs of ivermectin toxicity and the efficacy of antigabaergic convulsants as antidotes for ivermectin poisoning in epileptic chickens.
To assess the efficacy of the antiGABAergic convulsants, methyl-beta carboline-carboxylate (beta-CCM), picrotoxin and pentylenetetrazol (PTZ), as antidotes for ivermectin toxicity, 8 epileptic and 6 non-epileptic chickens/treatment group were given dosages of each convulsant which previously induced convulsions in 50% and again in 100% of treated chickens. Expand
Behavioral changes with alterations of choline acetyltransferase immunoreactivities induced by N-butyl benzenesulfonamide.
N-butyl benzenesulfonamide (NBBS), one of the sulfonamide plasticizers, induced characteristic effects to Wistar rats after acute repeated exposures that showed pica, staggering gait with hindlimb-paresis and splaying, teeth-grinding, self paw-biting and coma. Expand
2-[18F]-Fluoro-2-deoxy-D-glucose positron emission tomography as guidance for primary treatment in patients with advanced-stage resectable squamous cell carcinoma of the larynx and hypopharynx.
  • J. Roh, K. Pae, +5 authors S. Kim
  • Medicine
  • European journal of surgical oncology : the…
  • 1 August 2007
HighFDG uptake is associated with poor survival in patients with advanced laryngopharyngeal SCC and patients with high FDG uptake may be better treated by surgical resection followed by RT and chemotherapy. Expand
In vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons
Election of the extracellular K+ concentration in the amygdala for 70 min or longer without a recovery period produced extensive neuronal damage and edematous-appearing neuropil in the tissue dialysed, as well as loss of normal neurons. Expand