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A mechanically stabilized receptor–ligand flex-bond important in the vasculature
Haemostasis in the arteriolar circulation mediated by von Willebrand factor (VWF) binding to platelets is an example of an adhesive interaction that must withstand strong hydrodynamic forces actingExpand
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Force-induced on-rate switching and modulation by mutations in gain-of-function von Willebrand diseases
Significance Binding of von Willebrand factor (VWF) to platelets is regulated by hydrodynamic forces in the vasculature. VWF can sense force and can bind when the hydrodynamics change due toExpand
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Hydrothermal Synthesis of Single-Crystalline Zinc Glutarate and Its Structural Determination
The synthesis of single-crystalline zinc glutarate (sc-ZnGA) by the hydrothermal reactions of zinc perchlorate hexahydrate and glutaronitrile and determining of its structure are first reported.Expand
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Comparison of Angiogenic Activities of Three Neuropeptides, Substance P, Secretoneurin, and Neuropeptide Y Using Myocardial Infarction
BACKGROUND:The interplay between neurogenesis and angiogenesis is crucial during the development mediated by neuro-angiogenic morphogens. In particular, the angiogenic activity of neuropeptides andExpand
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Direct observation of ligand-induced receptor dimerization with a bioresponsive hydrogel
Multimerization of biomolecules is essential for biological function and thus there is a need for sensitive biochemical assays that determine whether a molecule associates with one or more otherExpand
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Modulating cardiomyocyte and fibroblast interaction using layer-by-layer deposition facilitates synchronisation of cardiac macro tissues.
Maturation and synchronisation of heart cells, including cardiomyocytes and fibroblasts, are essential to develop functional biomimetic cardiac tissues for regenerative medicine and drug discovery.Expand
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Effect of dimethylamine on the gas phase sulfuric acid concentration measured by Chemical Ionization Mass Spectrometry
Abstract Sulfuric acid is widely recognized as a very important substance driving atmospheric aerosol nucleation. Based on quantum chemical calculations it has been suggested that the quantitativeExpand
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Collagen Type I Containing Hybrid Hydrogel Enhances Cardiomyocyte Maturation in a 3D Cardiac Model
In vitro maturation of cardiomyocytes in 3D is essential for the development of viable cardiac models for therapeutic and developmental studies. The method by which cardiomyocytes undergoesExpand
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Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration.
Cells change migration patterns in response to chemical stimuli, including the gradients of the stimuli. Cellular migration in the direction of a chemical gradient, known as chemotaxis, plays anExpand