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  • Influence
A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies
Over the last decade, gene expression microarrays have had a profound impact on biomedical research. The diversity of platforms and analytical methods available to researchers have made theExpand
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Gene Expression–Based Recurrence Prediction of Hepatitis B Virus–Related Human Hepatocellular Carcinoma
Purpose: The poor prognosis of hepatocellular carcinoma (HCC) is, in part, due to the high rate of recurrence even after “curative resection” of tumors. Therefore, it is axiomatic that theExpand
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Knowledge boosting: a graph-based integration approach with multi-omics data and genomic knowledge for cancer clinical outcome prediction
TLDR
We propose a new graph-based integration framework for integrating multi-omics data and genomic knowledge to improve power in predicting clinical outcomes and elucidate interplay between different levels. Expand
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Comprehensive Analysis of Transcriptome Sequencing Data in the Lung Tissues of COPD Subjects
Background and Objectives. Chronic obstructive pulmonary disease (COPD) is a complex disease characterized by airflow limitation. Although airway inflammation and oxidative stress are known to beExpand
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Difference-based clustering of short time-course microarray data with replicates
  • J. Kim, J. Kim
  • Computer Science, Medicine
  • BMC Bioinformatics
  • 14 July 2007
TLDR
We propose a novel clustering algorithm for identifying a subset of genes sharing a significant temporal expression pattern when replicates are used. Expand
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Genomic evidence of reactive oxygen species elevation in papillary thyroid carcinoma with Hashimoto thyroiditis.
Elevated levels of reactive oxygen species (ROS) have been proposed as a risk factor for the development of papillary thyroid carcinoma (PTC) in patients with Hashimoto thyroiditis (HT). However, itExpand
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Histone deacetylase regulates high mobility group A2-targeting microRNAs in human cord blood-derived multipotent stem cell aging
Cellular senescence involves a reduction in adult stem cell self-renewal, and epigenetic regulation of gene expression is one of the main underlying mechanisms. Here, we observed that the cellularExpand
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Synergistic effect of different levels of genomic data for cancer clinical outcome prediction
TLDR
We propose an integrated framework that uses multi-level genomic data for prediction of clinical outcomes in brain cancer (glioblastoma multiforme, GBM) and ovarian cancer (serous cystadenocarcinoma). Expand
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Identifying set-wise differential co-expression in gene expression microarray data
TLDR
dCoxS is a two-step analysis method that identifies differentially coexpressed gene set pairs between conditions. Expand
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ArrayXPath: mapping and visualizing microarray gene-expression data with integrated biological pathway resources using Scalable Vector Graphics
TLDR
ArrayXPath produces Javascript-enabled SVGs for web-enabled interactive visualization of pathways integrated with gene-expression profiles. Expand
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