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Estimating classification error rate: Repeated cross-validation, repeated hold-out and bootstrap
- J. Kim
- Computer Science, Mathematics
- Comput. Stat. Data Anal.
- 1 September 2009
We consider the accuracy estimation of a classifier constructed on a given training sample. The naive resubstitution estimate is known to have a downward bias problem. The traditional approach to… Expand
Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor
- Jungsoon Lee, J. Kim, A. Biter, B. Sielaff, Sukyeong Lee, F. Tsai
- Medicine, Biology
- Proceedings of the National Academy of Sciences
- 6 May 2013
Heat shock protein (Hsp) 104 is a ring-forming, protein-remodeling machine that harnesses the energy of ATP binding and hydrolysis to drive protein disaggregation. Although Hsp104 is an active… Expand
Akt Is a Key Modulator of Endothelial Progenitor Cell Trafficking in Ischemic Muscle
Trafficking of transplanted endothelial progenitor cells (EPCs) to ischemic tissue is enhanced by stromal‐derived factor 1 (SDF‐1) and vascular endothelial growth factor (VEGF). However, it has not… Expand
Involvement of E-selectin in recruitment of endothelial progenitor cells and angiogenesis in ischemic muscle.
E-selectin plays critical roles in tethering leukocytes to endothelial cells (ECs). We studied the role of E-selectin in endothelial progenitor cell (EPC) homing and vasculogenesis. After ischemia,… Expand
Associations of organochlorine pesticides and polychlorinated biphenyls in visceral vs. subcutaneous adipose tissue with type 2 diabetes and insulin resistance.
Background exposure to organochlorine (OC) pesticides and polychlorinated biphenyls (PCBs) has been linked to type 2 diabetes. As OC pesticides and PCBs mainly accumulate in adipose tissue and there… Expand
Loss of beta-cells with fibrotic islet destruction in type 2 diabetes mellitus.
- J. Kim, Seung-Hyun B. Ko, +10 authors K. Yoon
- Medicine, Biology
- Frontiers in bioscience : a journal and virtual…
- 1 May 2008
Recent morphologic analyses of human pancreases strongly suggest that a decreased beta-cell mass is observed from the early stages of diabetes and is caused by accelerated apoptosis of the… Expand
Distributed knowledge in an online patient support community: Authority and discovery
- Michelle M. Kazmer, M. Lustria, +4 authors J. Frost
- Computer Science
- J. Assoc. Inf. Sci. Technol.
- 1 July 2014
Amyotrophic lateral sclerosis (ALS) is a progressively debilitating neurodegenerative condition that occurs in adulthood and targets the motor neurons. Social support is crucial to the well‐being and… Expand
Noninvasive diagnosis of ischemia-causing coronary stenosis using CT angiography: diagnostic value of transluminal attenuation gradient and fractional flow reserve computed from coronary CT…
OBJECTIVES The aim of this study was to compare the diagnostic performance of coronary computed tomography angiography (CCTA)-derived computed fractional flow reserve (FFR(CT)) and transluminal… Expand
Expression of wild-type and truncated myocilins in trabecular meshwork cells: their subcellular localizations and cytotoxicities.
- S. Sohn, W. Hur, +4 authors C. Kee
- Biology, Medicine
- Investigative ophthalmology & visual science
- 1 December 2002
PURPOSE To investigate the subcellular localizations and potential cytotoxicities of wild-type and truncated (Q368X) myocilin in cultured human trabecular meshwork (TM) cells. METHODS Full-length… Expand
Chorea-ballism associated with nonketotic hyperglycaemia or diabetic ketoacidosis: characteristics of 25 patients in Korea.
- S. Lee, Jeong-Ah Shin, +6 authors Yu-Bae Ahn
- Diabetes research and clinical practice
- 1 August 2011
Chorea-ballism is a rare form of movement disorder complicated by severe hyperglycaemia and in association with a contralateral basal ganglia lesion. We analysed the clinical characteristics of 25… Expand