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Reactive oxygen species mediated ginsenoside Rg3- and Rh2-induced apoptosis in hepatoma cells through mitochondrial signaling pathways.
Panax ginseng (P. ginseng) has anti-cancer effects in several cancer models. Ginsenosides are the main bioactive components in P. ginseng. Korean red ginseng (KRG) extract can potently kill variousExpand
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Effects of capsaicin on Ca(2+) release from the intracellular Ca(2+) stores in the dorsal root ganglion cells of adult rats.
We have investigated the effect of capsaicin on Ca(2+) release from the intracellular calcium stores. Intracellular calcium concentration ([Ca(2+)](i)) was measured in rat dorsal root ganglion (DRG)Expand
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Fluoxetine-induced apoptosis in hepatocellular carcinoma cells.
BACKGROUND In addition to being used to treat mental disorders, a serious complication of cancer, antidepressants have been reported to improve cancer patient immunity, inhibit cell growth and haveExpand
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The antioxidant, taurine reduced lipopolysaccharide (LPS)-induced generation of ROS, and activation of MAPKs and Bax in cultured pneumocytes.
Lipopolysaccharide (LPS) can cause damage to the epithelia of the respiratory tract. However, taurine can protect the lung tissue from such oxidant-induced inflammation. This study examined theExpand
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Ketamine-induced cardiac depression is associated with increase in [Mg2+]i and activation of p38 MAP kinase and ERK 1/2 in guinea pig.
This study investigated the signaling pathways responsible for ketamine-induced cardiac depression in guinea pigs. The left ventricular development pressure (LVDP), velocity of the change in pressureExpand
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Taurine reduces FK506-induced generation of ROS and activation of JNK and Bax in Madin Darby canine kidney cells
The immunosuppressive compound FK506 has been successfully used in kidney and liver transplant recipients. However, the compound can induce significant side effects on kidney function. Taurine is aExpand
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Relationships Between Blood Mg2+ and Energy Metabolites/Enzymes After Acute Exhaustive Swimming Exercise in Rats
Magnesium (Mg) plays a central role in neuronal activity, cardiac excitability, neuromuscular transmission, muscular contraction, vasomotor tone, and blood pressure, all of which are significantlyExpand
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Myocardial Calcification and Hypertension following Chronic Renal Failure and Ameliorative Effects of Furosemide and Captopril
Objectives: The aim of this study was to prevent metastatic myocardial calcification and hypertension following chronic renal failure (CRF). Methods: A total of 50 male Sprague-Dawley rats wereExpand
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Improvement of gas Transfer by Hemosome
Intravascular oxidation is a respiratory assist method used to treat acute respiratory distress syndrome (ARDS). However, intravascular oxidation through higher gas exchange is needed for successfulExpand
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Hepatoprotective effects of Nigella sativa seed extract against acetaminophen-induced oxidative stress.
OBJECTIVE To investigate the protective effects of Nigella sativa seed extract (NSSE) against acetaminophen (APAP)-induced hepatotoxicity in TIB-73 cells and rats. METHODS Toxicity in TIB-73 cellsExpand
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