• Publications
  • Influence
Comprehensive control of human papillomavirus infections and related diseases.
Infection with human papillomavirus (HPV) is recognized as one of the major causes of infection-related cancer worldwide, as well as the causal factor in other diseases. Strong evidence for a causalExpand
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Health and economic implications of HPV vaccination in the United States.
BACKGROUND The cost-effectiveness of prophylactic vaccination against human papillomavirus types 16 (HPV-16) and 18 (HPV-18) is an important consideration for guidelines for immunization in theExpand
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  • Open Access
Cost effectiveness analysis of including boys in a human papillomavirus vaccination programme in the United States
Objective To assess the cost effectiveness of including preadolescent boys in a routine human papillomavirus (HPV) vaccination programme for preadolescent girls. Design Cost effectiveness analysisExpand
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  • Open Access
Cost-effectiveness of alternative triage strategies for atypical squamous cells of undetermined significance.
CONTEXT Every year approximately 2 million US women are diagnosed as having a cervical cytological result of atypical squamous cells of undetermined significance (ASC-US). OBJECTIVE To determineExpand
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  • Open Access
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages
The macrophage‐mediated inflammatory response is a key etiologic component of obesity‐related tissue inflammation and insulin resistance. The transcriptional factor FoxO1 is a key regulator of cellExpand
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  • Open Access
Cost-Effectiveness of Human Papillomavirus DNA Testing for Cervical Cancer Screening in Women Aged 30 Years or More
OBJECTIVE: To evaluate the cost-effectiveness of human papillomavirus (HPV) DNA testing as a primary screening test in combination with cervical cytology in women aged 30 years or more. METHODS: AExpand
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TLR4 and Insulin Resistance
  • J. Kim, D. Sears
  • Medicine
  • Gastroenterology research and practice
  • 10 August 2010
Chronic inflammation is a key feature of insulin resistance and obesity. Toll-Like Receptor 4 (TLR4), involved in modulating innate immunity, is an important mediator of insulin resistance and itsExpand
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  • Open Access
Multiparameter calibration of a natural history model of cervical cancer.
The objective of this study was to develop a comprehensive natural history model of human papillomavirus (HPV) and cervical cancer using a two-step approach to model calibration. In the first step,Expand
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  • Open Access
Cost-effectiveness of HPV 16, 18 vaccination in Brazil.
We use an empirically calibrated model to estimate the cost-effectiveness of cervical cancer prevention in Brazil, a country with a high cervical cancer burden. Assuming 70% coverage, HPV 16, 18Expand
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  • Open Access
Noradrenergic modulation in the olfactory bulb influences spontaneous and reward‐motivated discrimination, but not the formation of habituation memory
The mammalian main olfactory bulb receives a significant noradrenergic input from the locus coeruleus. Norepinephrine is involved in acquisition of conditioned odor preferences in neonatal animalsExpand
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