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Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality.
CONTEXT Laboratory investigations suggest that exposure to hyperoxia after resuscitation from cardiac arrest may worsen anoxic brain injury; however, clinical data are lacking. OBJECTIVE To test… Expand
Significance of arterial hypotension after resuscitation from cardiac arrest*
Objective:Expert guidelines advocate hemodynamic optimization after return of spontaneous circulation (ROSC) from cardiac arrest despite a lack of empirical data on prevalence of post-ROSC… Expand
Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department.
OBJECTIVE Early goal-directed therapy (EGDT) has been shown to decrease mortality in patients with severe sepsis and septic shock. Consensus guidelines now advocate EGDT for the first 6 h of sepsis… Expand
Association Between Postresuscitation Partial Pressure of Arterial Carbon Dioxide and Neurological Outcome in Patients With Post–Cardiac Arrest Syndrome
- B. Roberts, J. Kilgannon, M. Chansky, N. Mittal, J. Wooden, S. Trzeciak
- 28 May 2013
Background— Partial pressure of arterial CO2 (PaCO2) is a regulator of cerebral blood flow after brain injury. Recent guidelines for the management of cardiac arrest recommend maintaining PaCO2 at 40… Expand
Association between initial prescribed minute ventilation and post-resuscitation partial pressure of arterial carbon dioxide in patients with post-cardiac arrest syndrome
AbstractBackgroundPost-cardiac arrest hypocapnia/hypercapnia have been associated with poor neurological outcome. However, the impact of arterial carbon dioxide (CO2) derangements during the… Expand
Multiple Organ Dysfunction After Return of Spontaneous Circulation in Postcardiac Arrest Syndrome
Objectives:Recent guidelines for the treatment of postcardiac arrest syndrome recommend optimization of vital organ perfusion after return of spontaneous circulation to reduce the risk of… Expand
Relationship Between Supranormal Oxygen Tension and Outcome After Resuscitation From Cardiac Arrest
Background— Laboratory and recent clinical data suggest that hyperoxemia after resuscitation from cardiac arrest is harmful; however, it remains unclear if the risk of adverse outcome is a threshold… Expand
Pediatric Post-Cardiac Arrest Care: A Scientific Statement From the American Heart Association.
Successful resuscitation from cardiac arrest results in a post-cardiac arrest syndrome, which can evolve in the days to weeks after return of sustained circulation. The components of post-cardiac… Expand
Association between chest compression rates and clinical outcomes following in-hospital cardiac arrest at an academic tertiary hospital.
- J. Kilgannon, M. Kirchhoff, L. Pierce, Nicholas Aunchman, S. Trzeciak, B. Roberts
AIMS Recent guidelines for management of cardiac arrest recommend chest compression rates of 100-120 compressions/min. However, animal studies have found cardiac output to increase with rates up to… Expand
Early arterial hypotension is common in the post-cardiac arrest syndrome and associated with increased in-hospital mortality.
AIM After return of spontaneous circulation (ROSC) from cardiac arrest, profound myocardial stunning and systemic inflammation may cause hemodynamic alterations; however, the prevalence of post-ROSC… Expand