• Publications
  • Influence
A test of neutrality based on interlocus associations.
  • J. Kelly
  • Biology, Medicine
  • Genetics
  • 1 July 1997
This work investigates the statistical properties of a measure of interlocus genetic associations under the assumption that mutations are selectively neutral and sites are completely linked, denoted ZnS, based on the squared correlation of allelic identity at pairs of polymorphic sites. Expand
Plant mating systems in a changing world.
A meta-analysis of 22 studies involving 27 plant species shows a significant reduction in the proportion of seeds outcrossed in response to anthropogenic habitat modifications, and whether reproductive assurance through selfing effectively compensates for reduced outcrossing is discussed. Expand
The Statistics of Bulk Segregant Analysis Using Next Generation Sequencing
A statistical framework for QTL mapping using bulk segregant analysis (BSA) based on high throughput, short-read sequencing is described and it is found that relatively large bulks maximize the power to detect QTLs even though this implies weaker selection and less extreme allele frequency differences. Expand
Direct estimation of the mutation rate at dinucleotide microsatellite loci in Arabidopsis thaliana (Brassicaceae)
A survey of dinucleotide repeats across the entire Arabidopsis genome indicates that AT repeats are most abundant, followed by CT, and CA, which is consistent with the stepwise mutation model of microsatellite evolution. Expand
Differential regulation of a MYB transcription factor is correlated with transgenerational epigenetic inheritance of trichome density in Mimulus guttatus.
It is found that parental leaf damage induces down-regulation of MYB MIXTA-like 8 in progeny, which is associated with epigenetically inherited increased trichome density. Expand
Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin
The discovery that allelic differences in DPG-sensitivity contribute to adaptive variation in hemoglobin–O2 affinity illustrates the value of integrating evolutionary analyses of sequence variation with mechanistic appraisals of protein function. Expand
Speciation by reinforcement: a model derived from studies of Drosophila.
It is suggested that an increase in the level of female mating discrimination can yield reinforcement without further divergence of either male characters or female preferences, and selection on mating discrimination is a viable mechanism for reinforcement and may allow speciation under less stringent conditions than selection on female preference. Expand
The pattern of phenotypic and genetic changes in this experiment favors a sequential model for the evolution of the multitrait “selfing syndrome” observed throughout angiosperms. Expand
Scaling up evolutionary responses to elevated CO2: lessons from Arabidopsis
This review synthesizes recent studies investigating the role of atmospheric CO2 as a selective agent on plants and provides a quantitative framework for scaling the evolutionary effects of CO2 on plants in order to determine changes in community and ecosystem productivity. Expand
Genotype × environment interaction for male attractiveness in an acoustic moth: evidence for plasticity and canalization
It is argued that variation persists in natural populations because G’× E interactions prevent any one variant from producing the optimal phenotype across all environments. Expand