J. Jose

Publications156
h-index28
Citations2,493
Highly Influential Citations76
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The Autodisplay Story, from Discovery to Biotechnical and Biomedical Applications
  • J. Jose, T. Meyer
  • Biology, Medicine
  • Microbiology and Molecular Biology Reviews
  • 1 December 2007
SUMMARY Among the pathways used by gram-negative bacteria for protein secretion, the autotransporter pathway represents a solution of impressive simplicity. Proteins are transported, independent of… Expand
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Autodisplay: efficient bacterial surface display of recombinant proteins
  • J. Jose
  • Biology, Medicine
  • Applied Microbiology and Biotechnology
  • 1 February 2006
To display a protein or peptide with a distinct function at the surface of a living bacterial cell is a challenging exercise with constantly increasing impact in many areas of biochemistry and… Expand
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Bacterial whole-cell biocatalysts by surface display of enzymes: toward industrial application
Despite the first report on the bacterial display of a recombinant peptide appeared almost 30 years ago, industrial application of cells with surface-displayed enzymes is still limited. To display an… Expand
  • 81
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Functional esterase surface display by the autotransporter pathway in Escherichia coli
Bacterial surface display is a promising tool for a wide variety of biotechnological applications. In this work, a carboxylesterase, EstA from Burkholderia gladioli was translocated to the surface of… Expand
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Autodisplay of Active Sorbitol Dehydrogenase (SDH) Yields a Whole Cell Biocatalyst for the Synthesis of Rare Sugars
Whole cell biocatalysts are attractive technological tools for the regio‐ and enantioselective synthesis of products, especially from substrates with several identical reactive groups. In the present… Expand
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Autodisplay of the protease inhibitor aprotinin in Escherichia coli.
  • J. Jose, D. Zangen
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 12 August 2005
The Kunitz type protease inhibitor aprotinin, containing three intramolecular disulfide bonds, was expressed on the surface of Escherichia coli by Autodisplay. For this purpose, the aprotinin gene… Expand
  • 46
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A carbon nanotube metal semiconductor field effect transistor-based biosensor for detection of amyloid-beta in human serum.
We have developed a carbon nanotube (CNT) film-based biosensor with a metal semiconductor field effect transistor structure (MESFET). A gold top gate was deposited on the middle of the CNT channel… Expand
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Naphthol AS-E Phosphate Inhibits the Activity of the Transcription Factor Myb by Blocking the Interaction with the KIX Domain of the Coactivator p300
The transcription factor c-Myb is highly expressed in hematopoietic progenitor cells and controls the transcription of genes important for lineage determination, cell proliferation, and… Expand
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TF--a novel cell-permeable and selective inhibitor of human protein kinase CK2 induces apoptosis in the prostate cancer cell line LNCaP.
BACKGROUND Abnormally high activity of protein kinase CK2 is linked to various diseases including cancer. Therefore, the inhibition of CK2 is a promising therapeutic strategy to fight this disease.… Expand
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Lignocellulases: a review of emerging and developing enzymes, systems, and practices
The highly acclaimed prospect of renewable lignocellulosic biocommodities as obvious replacement of their fossil-based counterparts is burgeoning within the last few years. However, the use of the… Expand
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