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Investigating biological activity spectrum for novel quinoline analogues.
The lack of the wide spectrum of biological data is an important obstacle preventing the efficient molecular design. Quinoline derivatives are known to exhibit a variety of biological effects. In theExpand
A new modification of anti-tubercular active molecules.
The connection of two active molecules across an easily released bridge as a new type of potentially active molecule has been studied. The synthesis is based on derivatives that originate fromExpand
Designing a dynamic dissolution method: a review of instrumental options and corresponding physiology of stomach and small intestine.
Development of new pharmaceutical compounds and dosage forms often requires in vitro dissolution testing with the closest similarity to the human gastrointestinal (GI) tract. To create suchExpand
Application Of Nanotechnology In Agriculture And Food Industry, Its Prospects And Risks
Abstract Nanoagrochemicals, such as nanopesticides, nanofertilizers or plant growth stimulating nanosystems, were primarily designed to increase solubility, enhance bioavailability, targetedExpand
Primary Investigation of the Preparation of Nanoparticles by Precipitation
The absorption, distribution, biotransformation and excretion of a drug involve its transport across cell membranes. This process is essential and influenced by the characteristics of the drug,Expand
Transdermal Application of Drugs and Techniques Affecting Skin Barrier
The development in the field of pharmaceutical dosage forms results in discovery of additional highly sophisticated drug delivery systems that allow maintaining constant level of active substance inExpand
Synthesis and antimicrobial evaluation of new 2-substituted 5,7-di-tert-butylbenzoxazoles.
Various synthetic pathways of the 30 novel 2-substituted 5,7-di-tert-butylbenzoxazoles as new potential antimicrobial drugs are discussed. The 28 intermediates are described as well. The compoundsExpand
Antifungal properties of new series of quinoline derivatives.
The series of quinoline derivatives were prepared. The synthetic approach, analytical, and spectroscopic data of all synthesized compounds are presented. All the prepared derivatives were analyzedExpand
Azone analogues: classification, design, and transdermal penetration principles
The development in the field of pharmaceutical dosage forms results in the discovery of additional highly sophisticated drug delivery systems that allow maintaining a constant level of the activeExpand
Rhodanineacetic Acid Derivatives as Potential Drugs: Preparation, Hydrophobic Properties and Antifungal Activity of (5-Arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic Acids †
Some [(5Z)-(5-arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)]acetic acids were prepared as potential antifungal compounds. The general synthetic approach to all synthesized compounds isExpand
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