J. Jain

Publications56
h-index11
Citations387
Highly Influential Citations11
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Design, synthesis and biological evaluation of 1,3,4-oxadiazole derivatives.
3D QSAR analysis for the 21 molecules of 1,3,4-oxadiazoles was carried out by using k-Nearest Neighbor Molecular Field Analysis (kNN-MFA) combined with various selection procedures. 30 3D QSAR models… Expand
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Multiple genus-specific markers in PCR assays improve the specificity and sensitivity of diagnosis of brucellosis in field animals.
Brucella-specific nucleotide sequences encoding the BCSP 31 kDa protein, Omp2 and the 16S rRNA were employed in three independent diagnostic PCR assays. Results of the three PCR assays on six… Expand
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Nicotinic acid hydrazones: a novel anticonvulsant pharmacophore
A series of aryl acid hydrazones of substituted aromatic acid hydrazides (D1 to D20) were synthesised and evaluated for anticonvulsant activity. Aryl acid hydrazones of Nicotinic acid hydrazide (D8,… Expand
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Menthone aryl acid hydrazones: a new class of anticonvulsants.
A series of ten compounds (Compounds J(1)-J(10)) of (±) 3-menthone aryl acid hydrazone was synthesized and characterized by thin layer chromatography and spectral analysis. Synthesized compounds were… Expand
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Study of Convolvulus pluricaulis for antioxidant and anticonvulsant activity.
Convolvulus pluricaulis Choisy is a perennial wild herb commonly found on sandy & rocky areas under xerophytic conditions in northern India. It is a reputed drug of ayurveda and reported to posses… Expand
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Anticonvulsant and neurotoxicity evaluation of some N(4) phenyl substituted pyridyl semicarbazones.
A series of 4-aryl substituted semicarbazones of pyridyl carbaldehyde and pyridyl methyl ketone were designed and synthesized to meet the structural requirements essential for anticonvulsant… Expand
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Synthesis and screening of substituted thiosemicarbazone derivatives: an approach towards novel anticonvulsant search.
A series of thiosemicarbazones of halogen substituted benzaldehydes, benzophenone and acetophenone were synthesized using an appropriate synthetic route and characterized by thin layer chromatography… Expand
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DESIGN OF NEW PEROXISOME PROLIFERATORS GAMMA ACTIVATED RECEPTOR AGONISTS (PPARγ) VIA QSAR BASED MODELING
"Introduction: The Peroxisome proliferators-activated receptors (PPARs) are one of the nuclear fatty acid receptors, which contain a type II zinc finger DNA binding pattern and a hydrophobic ligand… Expand
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Design and Evaluation of Semicarbazones and Thiosemicarbazones as Novel Anticonvulsants
A series of semicarbazones and thiosemicarbazones were designed and synthesized to meet the structural requirements essential for anticonvulsant activity. All the compounds were evaluated for… Expand
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Menthone semicarbazides and thiosemicarbazides as anticonvulsant agents.
A series of novel (+/-) 3-menthone semi carbazides (1-7) and thiosemicarbazides synthesized using an appropriate synthetic route and characterized by thin layer chromatography and spectral analysis.… Expand
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