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Immunogenicity and Reactogenicity of Four Doses of Diphtheria-Tetanus-Three-Component Acellular Pertussis-Hepatitis B-Inactivated Polio Virus-Haemophilus influenzae Type b Vaccine Coadministered with
Coadministration of the DTPa-HBV-IPV/Hib and 7vPn vaccines at separate injection sites during the same vaccination visit was effective and safe. Expand
Decennial administration of a reduced antigen content diphtheria and tetanus toxoids and acellular pertussis vaccine in young adults.
A second dTpa booster was highly immunogenic and well tolerated in this population of young adults and supports the use of this vaccine as a decennial booster. Expand
Review of 8 years of experience with Infanrix hexa™ (DTPa–HBV–IPV/Hib hexavalent vaccine)
Data show DTPa–HBV–IPV/Hib to be highly immunogenic and well tolerated across a range of different primary and booster vaccination schedules, as well as when administered concomitantly with other licensed vaccines (e.g., pneumococcal conjugate vaccine). Expand
Booster immunization with a hexavalent diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated poliovirus vaccine and Haemophilus influenzae type b conjugate combination vaccine in the
The combined hexavalent DTPa-HBV-IPV/Hib vaccine is immunogenic and safe when used for boosting in the second year of life, regardless of the primary vaccine used, and offers sustained protection during early childhood and beyond. Expand
Immunogenicity and Reactogenicity of Primary Immunization With a Hexavalent Diphtheria-Tetanus-Acellular Pertussis-Hepatitis B-Inactivated Polio-Haemophilus Influenzae Type B Vaccine Coadministered
Coadministration of DTaP-HBV-IPV/Hib or DTap-IPv/H Hib with 2 doses of MenC-TT conjugate vaccine is safe, well tolerated, and immunogenic, with no impairment of the response to the coadministered antigens. Expand
Lasting immune memory against hepatitis B in children after primary immunization with 4 doses of DTPa-HBV-IPV/Hib in the first and 2nd year of life
The combined DTPa-HBV-IPV/Hib vaccine induced lasting immune memory against hepatitis B, likely to be similar to that observed following priming with monovalent HBV vaccines. Expand
Persistence of antibodies and immune memory to hepatitis B vaccine 20 years after infant vaccination in Thailand.
Higher persisting seroprotection rates in subjects boosted at Year 5 did not translate into apparent differences in immune memory in a high endemic country, as assessed 20 years after priming with a recombinant HBV-vaccine during infancy. Expand
A decennial booster dose of reduced antigen content diphtheria, tetanus, acellular pertussis vaccine (Boostrix™) is immunogenic and well tolerated in adults.
This study supports replacing traditional Td boosters with dTpa, and use of Boostrix™ as a decennial booster, and well tolerated without serious adverse events, consistent with product experience. Expand
Immunogenicity and reactogenicity of DTPa‐HBV‐IPV/Hib vaccine as primary and booster vaccination in low‐birth‐weight premature infants
Aim: To assess suitability of a combined DTPa‐HBV‐IPV/Hib vaccine (Infanrix hexa™) for immunization of low‐birth‐weight (<2.0 kg) preterm infants, with particular focus on the hepatitis B response.
A comparison of booster immunisation with a combination DTPa-IPV vaccine or DTPa plus IPV in separate injections when co-administered with MMR, at age 4-6 years.
This combined DTPa-IPV vaccine has a similar reactogenicity profile to DTPA, is immunogenic when given as a booster dose at 4-6 years of age, and has no impact on the immunogenicity of a co-administered second dose of MMR vaccine. Expand