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Role of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference.
Narp knockout (KO) mice demonstrate an impaired extinction of morphine conditioned place preference (CPP). Because the medial prefrontal cortex (mPFC) has been implicated in extinction learning, we… Expand
Evaluation of similar quality attribute characteristics in SB5 and reference product of adalimumab
ABSTRACT Biosimilars are biologic products that are highly similar to a licensed reference product in terms of quality, safety, and efficacy. SB5 is a biosimilar of Humira® (adalimumab) developed by… Expand
Glycosylation profile and biological activity of Remicade® compared with Flixabi® and Remsima®
ABSTRACT As biosimilars enter the market, comparisons of product quality are needed. Manufacturing differences may lead to differences in critical quality attributes, which affect efficacy.… Expand
Demonstration of functional similarity of a biosimilar adalimumab SB5 to Humira®.
- J. J. Lee, Junmo Yang, C. Lee, Youngjin Moon, S. Ahn, Jiyoon Yang
- Chemistry, Medicine
- Biologicals : journal of the International…
- 1 March 2019
A biosimilar is a biological medicinal product that is highly similar to an authorized biological product in terms of quality, biological activity, safety and efficacy. SB5 was developed by Samsung… Expand
Narp knockout mice show normal reactivity to novelty but attenuated recovery from neophobia
- A. Blouin, J. J. Lee, B. Tao, D. Smith, I. Reti
- Psychology, Medicine
- Behavioural Brain Research
- 15 November 2013
Narp knockout (KO) mice demonstrate cognitive inflexibility and addictive behavior, which are associated with abnormal reactivity to a novel stimulus. To assess reactivity to novelty, we tested Narp… Expand