J. Irwin

Publications69
h-index28
Citations2,830
Highly Influential Citations132
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High efficiency DNA extraction from bone by total demineralization.
In historical cases, missing persons' identification, mass disasters, and ancient DNA investigations, bone and teeth samples are often the only, and almost always the best, biological material… Expand
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Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians
We have sequenced the entire mtDNA genome (mtGenome) of 241 individuals who match 1 of 18 common European Caucasian HV1/HV2 types, to identify sites that permit additional forensic discrimination. We… Expand
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Mitochondrial control region sequences from a Vietnamese population sample
Entire mitochondrial control region data were generated for 187 individuals from Vietnam. These samples have been previously typed for 16 autosomal short-tandem repeats (STRs) [1].
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Failure of the ILD to determine data combinability for slow loris phylogeny.
Tests for incongruence as an indicator of among-data partition conflict have played an important role in conditional data combination. When such tests reveal significant incongruence, this has been… Expand
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Mitochondrial DNA control region sequences from Nairobi (Kenya): inferring phylogenetic parameters for the establishment of a forensic database
Large forensic mtDNA databases which adhere to strict guidelines for generation and maintenance, are not available for many populations outside of the United States and western Europe. We have… Expand
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Mitochondrial control region sequences from an Egyptian population sample.
Entire mitochondrial control region data was generated for 277 unrelated Egyptian individuals. High-throughput robotics, a redundant sequencing approach, and several quality control checks were… Expand
  • 46
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Mitochondrial DNA heteroplasmy in the emerging field of massively parallel sequencing
Highlights • We provide an update on developments in mtDNA forensic genetics.• We review the recent literature for the detection of heteroplasmy using next generation sequencing techniques.• We… Expand
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Mitochondrial control region sequences from northern Greece and Greek Cypriots
Entire mitochondrial control region data were generated for population samples of 319 unrelated individuals from northern Greece and 91 unrelated individuals from Cyprus. The samples from northern… Expand
  • 54
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DNA Commission of the International Society for Forensic Genetics: revised and extended guidelines for mitochondrial DNA typing.
The DNA Commission of the International Society of Forensic Genetics (ISFG) regularly publishes guidelines and recommendations concerning the application of DNA polymorphisms to the question of human… Expand
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Full mtGenome reference data: development and characterization of 588 forensic-quality haplotypes representing three U.S. populations.
Though investigations into the use of massively parallel sequencing technologies for the generation of complete mitochondrial genome (mtGenome) profiles from difficult forensic specimens are well… Expand
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