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Experimental chemotherapy with Allium sativum (Liliaceae) methanolic extract in rodents infected with Leishmania major and Leishmania donovani.
BACKGROUND & OBJECTIVES Several plant products have been tested and found to possess antileishmanial activity. The present study was undertaken to establish whether methanolic extract of AlliumExpand
Anti-parasitic activity and cytotoxicity of selected medicinal plants from Kenya.
Indigenous rural communities in the tropics manage parasitic diseases, like malaria and leishmaniasis, using herbal drugs. The efficacy, dosage, safety and active principles of most of the herbalExpand
In vitro effects of Warburgia ugandensis, Psiadia punctulata and Chasmanthera dependens on Leishmania major promastigotes.
Plant extracts from Warburgia ugandensis Sprague (Family: Canellaceae), Psiadia punctulata Vatke (Family: Compositae) and Chasmanthera dependens Hoschst (Family: Menispermaceae) were tested forExpand
Effects of glucocorticoids in Leishmania major infection
Leishmania parasites activate NF-κB which induces Th2 expression and inactivates Th1 genes thus subverting the host defense response and promotes the survival and development of the parasite inExpand
Comparative Analysis of the Effectiveness of Sand Fly Traps with Different Baits
Sand flies are small haematophagous insects that transmit Leishmania parasites. Infection with Leishmania parasites results in diseases known as leishmaniases which can be grouped into three mainExpand
Combination and monotherapy of Leishmania major infection in BALB/c mice using plant extracts and herbicides.
BACKGROUND & OBJECTIVES Leishmaniasis is a growing health problem in many parts of the world. Efforts to find new chemotherapeutics for leishmaniasis remain a priority. This study was carried out toExpand
Combination therapy using Pentostam and Praziquantel improves lesion healing and parasite resolution in BALB/c mice co-infected with Leishmania major and Schistosoma mansoni
BackgroundMost natural host populations are exposed to a diversity of parasite communities and co-infection of hosts by multiple parasites is commonplace across a diverse range of systems.Expand
In vitro antileishmanial activity and phytochemical analysis of Carissa edulis against Leishmania major
Background: However, there is need to carry out scientific studies in order to confirm the medicinal properties of many plants used traditionally. Carissa edulis Forskk. (Gentiales: Apocynaceae) usedExpand
In vitro and in vivo activities of blends of crude aqueous extracts from Allium sativum L, Callistemon citrinus (Curtis) Skeels and Moringa stenopetala (Baker F) Cufodontis against Leishmania major
Leishmania major caused cutaneous leishmaniasis leads to painful skin so res in humans and usual drugs are expensive, toxic, and require prolonged use. The in vitro and in vivo efficacy of aqueousExpand
Repellent effects of the essential oils of Cymbopogon citratus and Tagetes minuta on the sandfly, Phlebotomus duboscqi
BackgroundThe sandfly, Phlebotomus duboscqi is a vector of zoonotic cutaneous leishmaniasis (ZCL) that is an important public health problem in Eastern Africa. Repellents have been used forExpand