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Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity
TLDR
The data suggest that BRS-3 is required for the regulation of endocrine processes and metabolism responsible for energy balance and adiposity, and provides a useful new model for the investigation of human obesity and associated diseases. Expand
Neonatal Exposure to Sevoflurane Induces Abnormal Social Behaviors and Deficits in Fear Conditioning in Mice
TLDR
This study shows that exposure of neonatal mice to inhaled sevoflurane could cause not only learning deficits but also abnormal social behaviors resembling autism spectrum disorder. Expand
The functional neuroanatomy of corticotropin-releasing factor.
TLDR
Understanding of the central distribution of CRF has been provided by the recognition that most CRF antisera cross-react with an amidated dipeptide encoded by the melanin-concentrating hormone precursor, and by the likelihood that some central sites ofCRF peptide expression may be muted or masked by the presence of a CRF-binding protein (CRF-BP). Expand
Regulation of c-maf gene expression by Pax6 in cultured cells.
TLDR
In situ hybridization histochemical detection of Pax6 and c-Maf in the E14 lens showed that both mRNAs are expressed in the lens equator where lens epithelial cells are differentiating to lens fiber cells. Expand
Expression of Corticotropin-Releasing Hormone Type 1 Receptor in Paraventricular Nucleus after Acute Stress
TLDR
It is demonstrated that acute stress increases neuronal activation andCRH-R1 mRNA expression primarily in CRH-producing neurons of the parvocellular PVN, that CRH/R1 message is translated to CRH_R1 protein, and that PVN neurons are activated at least in part through CRH+R1 under acute stress. Expand
Maternal epidermal growth factor deficiency causes fetal hypoglycemia and intrauterine growth retardation in mice: possible involvement of placental glucose transporter GLUT3 expression.
TLDR
The results indicate that EGF plays an important role in fetal growth by regulating the transplacental supply of glucose via GLUT3 expression in the placenta through the expression ofGLUT3 mRNA without affecting GLUT1 mRNA levels. Expand
Differential expression of c-fos mRNA in rat retinal cells: Regulation by light/dark cycle
TLDR
Since a 30 min pulse of light during the dark period decreased c- fos expression in the outer nuclear layer, whereas a similar pulse of darkness during the light period resulted in an increase, environmental light/dark cues are also suggested to influence c-fos gene expression. Expand
Light‐Induced CREB Phosphorylation and Gene Expression in Rat Retinal Cells
TLDR
The signal pathway for light‐induced expression of c‐fos and the neuropeptide somatostatin in rat retinal cells was investigated and the colocalization of phosphorylated CREB at Ser133 and CaM kinase II in the neural retina was indicated. Expand
Corticotropin-releasing factor up-regulates its own receptor mRNA in the paraventricular nucleus of the hypothalamus.
TLDR
CRF may modulate CRF production and release from the PVN, by regulating CRF1-R expression, and the effect of stress, as a stimulant of endogenous CRF secretion, on mRNA accumulation is determined. Expand
Rat maf related genes: specific expression in chondrocytes, lens and spinal cord
TLDR
Comparison of the sequence homologies of the proteins encoded by maf-1 and mf-2 with those of c-maf and chicken mafB indicated that maf/maf-2 are the rat homologues of maf B and c- maf, respectively. Expand
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