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Epidemiology and causes of preterm birth
TLDR
A short cervical length and a raised cervical-vaginal fetal fibronectin concentration are the strongest predictors of spontaneous preterm birth. Expand
The length of the cervix and the risk of spontaneous premature delivery. National Institute of Child Health and Human Development Maternal Fetal Medicine Unit Network.
TLDR
The risk of spontaneous preterm delivery is increased in women who are found to have a short cervix by vaginal ultrasonography during pregnancy. Expand
Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate
Preterm delivery before 37 completed weeks gestation remains the major factor influencing infant mortality in developed countries. Women who have had a spontaneous preterm delivery are at much higherExpand
Primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth
TLDR
Advances in primary and secondary care, following strategies used for other complex health problems, such as cervical cancer, will be needed to prevent prematurity-related illness in infants and children. Expand
Depressive symptoms are associated with elevated serum proinflammatory cytokines among pregnant women
TLDR
Ass associations among perceived stress, depressive symptoms, and serum inflammatory markers in a sample of 60 pregnant women indicate that depressive symptoms are associated with higher levels of maternal seruminflammatory markers during pregnancy, consistent with the contention that depressive Symptoms may contribute to negative perinatal outcomes via inflammatory pathways. Expand
A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy.
TLDR
Fetal exposure to magnesium sulfate before anticipated early preterm delivery did not reduce the combined risk of moderate or severe cerebral palsy or death, although the rate of cerebral palsies was reduced among survivors. Expand
A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy
TLDR
This case-control study was the first to show a decrease in the incidence of cerebral palsy in the offspring of women who were given magnesium sulfate before preterm delivery, and is consistent with previous reports that antenatal magnesium sulfates does not reduce the combined risk of death or moderate or severe cerebral palsies, but may reduce the risk of cortex palsy among survivors. Expand
Research agenda for preterm birth: recommendations from the March of Dimes.
TLDR
The March of Dimes Scientific Advisory Committee created this prioritized research agenda, aimed at garnering serious attention and expanding resources to make major inroads into the prevention of PTB, targeting six major, overlapping categories: epidemiology, genetics, disparities, inflammation, biologic stress, and clinical trials. Expand
The preterm prediction study: significance of vaginal infections. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.
TLDR
The presence of bacterial vaginosis at 28 weeks' gestation is associated with an increased risk of spontaneous preterm birth and detection of Trichomonas vaginalis (by wet mount) or monilia (by potassium hydroxide preparation) had no significant associations with pretermBirth. Expand
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