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Childhood functional gastrointestinal disorders: child/adolescent.
The Rome II pediatric criteria for functional gastrointestinal disorders (FGIDs) were defined in 1999 to be used as diagnostic tools and to advance empirical research. In this document, the Rome IIIExpand
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The treatment-naive microbiome in new-onset Crohn's disease.
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked to host pathways that implicate an underlying role for aberrant immune responses to intestinal microbiota.Expand
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Development and validation of a pediatric Crohn's disease activity index.
Clinical and laboratory observations of 133 children and adolescents with Crohn's disease were used to validate an index of severity of illness previously developed by a group of senior pediatricExpand
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Childhood functional gastrointestinal disorders
This is the first attempt at defining criteria for functional gastrointestinal disorders (FGIDs) in infancy, childhood, and adolescence. The decision-making process was as for adults and consisted ofExpand
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Pediatric modification of the Montreal classification for inflammatory bowel disease: The Paris classification
Background: Crohn's disease and ulcerative colitis are complex disorders with some shared and many unique predisposing genes. Accurate phenotype classification is essential in determining the utilityExpand
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Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children.
BACKGROUND AND AIMS The REACH study evaluated the safety and efficacy of infliximab in children with moderately to severely active Crohn's disease. METHODS Patients (n = 112) with a PediatricExpand
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Abdominal pain and irritable bowel syndrome in adolescents: a community-based study.
OBJECTIVES This study was undertaken to determine (1) the prevalence of gastrointestinal symptoms including abdominal pain in a community-based population of adolescents, (2) whether a subgroup ofExpand
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Functional gastrointestinal disorders.
  • J. Hyams
  • Medicine
  • Current opinion in pediatrics
  • 1 October 1999
When clinicians label a child as having a functional disorder, there is often a pejorative connotation that the symptoms are psychological, imagined, or faked. These symptoms range from chronicExpand
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Evaluation of the Pediatric Crohn Disease Activity Index: A Prospective Multicenter Experience
Background and Objectives: Longitudinal assessment of disease activity is necessary for studies of therapeutic intervention in children with Crohn disease. The Pediatric Crohn Disease Activity IndexExpand
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Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.
Interactions between the host and gut microbial community likely contribute to Crohn disease (CD) pathogenesis; however, direct evidence for these interactions at the onset of disease is lacking.Expand
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