Author pages are created from data sourced from our academic publisher partnerships and public sources.
The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication.
- P. Bercik, A. Park, +14 authors E. Verdu
- Neurogastroenterology and motility : the official…
- 1 December 2011
BACKGROUND The probiotic Bifidobacterium longum NCC3001 normalizes anxiety-like behavior and hippocampal brain derived neurotrophic factor (BDNF) in mice with infectious colitis. Using a model of… Expand
Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors.
- K. Sircar, B. Hewlett, J. Huizinga, K. Chorneyko, I. Berezin, R. Riddell
- Medicine, Biology
- The American journal of surgical pathology
- 1 April 1999
Interstitial cells of Cajal (ICC) are implicated in the regulation of gut peristalsis and are immunostained by antibodies against Kit (CD117), a tyrosine kinase receptor. Most gastrointestinal… Expand
Assessment of gastric emptying using a low fat meal: establishment of international control values
OBJECTIVE:The diagnosis of gastroparesis implies delayed gastric emptying. The diagnostic gold standard is scintigraphy, but techniques and measured endpoints vary widely among institutions. In this… Expand
Regulation of slow wave frequency by IP(3)-sensitive calcium release in the murine small intestine.
- J. Malysz, G. Donnelly, J. Huizinga
- Chemistry, Medicine
- American journal of physiology. Gastrointestinal…
- 1 March 2001
Slow waves determine frequency and propagation characteristics of contractions in the small intestine, yet little is known about mechanisms of slow wave regulation. We propose a role for… Expand
Developmental origin and kit‐dependent development of the interstitial cells of cajal in the mammalian small intestine
- M. Klüppel, J. Huizinga, J. Malysz, A. Bernstein
- Biology, Medicine
- Developmental dynamics : an official publication…
- 1 January 1998
Interstitial cells of Cajal (ICCs) form a network of cells between the external longitudinal and circular muscle layers at the level of the Auerbach's plexus in the mammalian small intestine. These… Expand
Gastric Electrical Stimulation in Intractable Symptomatic Gastroparesis
Background: The treatment of gastroparesis remains unsatisfactory despite prokinetic and anti-emetic drugs. Gastric electrical stimulation has been proposed as a therapeutic option. We have assessed… Expand
Interstitial cells of Cajal generate a rhythmic pacemaker current
Networks of interstitial cells of Cajal embedded in the musculature of the gastrointestinal tract are involved in the generation of electrical pacemaker activity for gastrointestinal motility1,2.… Expand
Gastrointestinal stromal tumors may originate from a subset of CD34-positive interstitial cells of Cajal.
- T. Robinson, K. Sircar, B. Hewlett, K. Chorneyko, R. Riddell, J. Huizinga
- Biology, Medicine
- The American journal of pathology
- 1 April 2000
Most gastrointestinal stromal tumors (GISTs), a subgroup of mesenchymal neoplasms of the gut wall, express both Kit (CD117) and CD34 proteins. It has been suggested that GISTs originate from or… Expand
Gut peristalsis is governed by a multitude of cooperating mechanisms.
Peristaltic motor activity of the gut is an essential activity to sustain life. In each gut organ, a multitude of overlapping mechanisms has developed to acquire the ability of coordinated… Expand
Two Independent Networks of Interstitial Cells of Cajal Work Cooperatively with the Enteric Nervous System to Create Colonic Motor Patterns
- J. Huizinga, S. Martz, V. Gil, Xuanyu Wang, M. Jimenez, S. Parsons
- Psychology, Medicine
- Front. Neurosci.
- 5 August 2011
Normal motility of the colon is critical for quality of life and efforts to normalize abnormal colon function have had limited success. A better understanding of control systems of colonic motility… Expand