Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Urolithiasis and bladder carcinogenicity of melamine in rodents.
- R. Melnick, G. Boorman, J. Haseman, R. Montali, J. Huff
- Medicine
- Toxicology and applied pharmacology
- 1 February 1984
Melamine (2,4,6-triamino-s-triazine) was administered in the diet to F344 rats or B6C3F1 mice for 13 weeks (subchronic) or for 103 weeks (chronic) to determine its toxicologic profile, including… Expand
Carcinogenicity of 1,3-butadiene in C57BL/6 x C3H F1 mice at low exposure concentrations.
- R. Melnick, J. Huff, B. Chou, R. Miller
- Medicine
- Cancer research
- 15 October 1990
The carcinogenicity of inhaled 1,3-butadiene was evaluated in C57BL/6 x C3H F1 mice exposed to concentrations of this gas ranging from 6.25 to 625 ppm. Butadiene is a high production volume chemical,… Expand
Use of Historical Control Data in Carcinogenicity Studies in Rodents
- J. Haseman, J. Huff, G. Boorman
- Medicine
- Toxicologic pathology
- 1 February 1984
This paper considers the use of historical control data in the evaluation of tumor incidences from carcinogenicity studies in rodents. Although the most appropriate control group for interpretative… Expand
Fundamental Flaws of Hormesis for Public Health Decisions
- K. Thayer, R. Melnick, K. Burns, Devra Davis, J. Huff
- Psychology, Medicine
- Environmental health perspectives
- 15 June 2005
Hormesis (defined operationally as low-dose stimulation, high-dose inhibition) is often used to promote the notion that while high-level exposures to toxic chemicals could be detrimental to human… Expand
The Case for a Global Ban on Asbestos
- J. LaDou, B. Castleman, +13 authors A. Watterson
- Medicine
- Environmental health perspectives
- 1 July 2010
BACKGROUND
All forms of asbestos are now banned in 52 countries. Safer products have replaced many materials that once were made with it. Nonetheless, many countries still use, import, and export… Expand
Long-term chemical carcinogenesis experiments for identifying potential human cancer hazards: collective database of the National Cancer Institute and National Toxicology Program (1976-1991).
- J. Huff, J. Haseman
- Medicine
- Environmental health perspectives
- 1 December 1991
The carcinogenicity database used for this paper originated in the late 1960s by the National Cancer Institute (NCI) and since 1978 has been continued and made more comprehensive by the National… Expand
Cadmium-induced Cancers in Animals and in Humans
- J. Huff, R. Lunn, M. Waalkes, L. Tomatis, P. Infante
- Biology, Medicine
- International journal of occupational and…
- 1 April 2007
Abstract Discovered in the early 1800s, the use of cadmium and various cadmium salts started to become industrially important near the close of the 19th century, rapidly thereafter began to flourish,… Expand
Arsenic carcinogenesis in animals and in humans: Mechanistic, experimental, and epidemiological evidence
- P. C. Chan, J. Huff
- Medicine
- 1 November 1997
The Limits of Two-Year Bioassay Exposure Regimens for Identifying Chemical Carcinogens
- J. Huff, M. Jacobson, D. Davis
- Chemistry, Medicine
- Environmental health perspectives
- 30 June 2008
Background Chemical carcinogenesis bioassays in animals have long been recognized and accepted as valid predictors of potential cancer hazards to humans. Most rodent bioassays begin several weeks… Expand
Scientific concepts, value, and significance of chemical carcinogenesis studies.
- J. Huff, J. Haseman, D. Rall
- Business, Medicine
- Annual review of pharmacology and toxicology
- 1991
Synthetic chemicals and those naturally occurring chemicals that have be come 'man-made' via chemical synthesis and high volume production have only relatively recently been introduced into our way… Expand