Vasopeptidase inhibition prevents nephropathy in Zucker diabetic fatty rats.
- S. Schäfer, W. Linz, H. Rütten
- Medicine, BiologyCardiovascular Research
- 1 November 2003
Impaired left ventricular relaxation in type 2 diabetic rats is related to myocardial accumulation of Nɛ‐(carboxymethyl) lysine
- S. Schäfer, J. Huber, C. Wihler, H. Rütten, A. Busch, W. Linz
- Biology, MedicineEuropean Journal of Heart Failure
- 1 January 2006
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition
- C. Wihler, S. Schäfer, J. Huber
- Medicine, BiologyDiabetologia
- 12 July 2005
Improved AGE clearance and direct inhibition of AGE formation by chelation may contribute to reduced accumulation of renal AGEs and to the nephroprotective effects of vasopeptidase inhibition in type 2 diabetes.
Acute effect of different antidepressants on glycemia in diabetic and non-diabetic rats.
- R. Gomez, J. Huber, G. Tombini, H. Barros
- Medicine, BiologyBrazilian journal of medical and biological…
- 2001
Data raise the question of whether sertraline is the best choice for prolonged use for diabetic individuals, because of its antihyperglycemic effects, and whether clonazepam would be useful in cases with potential risk of hypoglycemia.
Differential effects of “Advanced glycation endproducts” and β-amyloid peptide on glucose utilization and ATP levels in the neuronal cell line SH-SY5Y
- B. Kuhla, C. Loske, S. Garcia de Arriba, R. Schinzel, J. Huber, G. Münch
- BiologyJournal of neural transmission
- 1 March 2004
Comparisons of the effects of a model-AGE and Aβ on cell viability, ATP level, glucose consumption and lactate production in the neuroblastoma cell line SH-SY5Y show that both AGEs and A β can cause differential disturbances in neuronal metabolism.
Dietary Bread Crust Advanced Glycation End Products Bind to the Receptor for AGEs in HEK‐293 Kidney Cells but Are Rapidly Excreted after Oral Administration to Healthy and Subtotally Nephrectomized…
- V. Somoza, M. Lindenmeier, K. Šebeková
- BiologyAnnals of the New York Academy of Sciences
- 1 June 2005
Abstract: In renal HEK‐293 cells, the dietary Maillard reaction compounds casein‐linked Nε‐carboxymethyllysine (CML), CML, bread crust (BC), and pronyl‐glycine (a key compound formed in association…
Plasma insulin levels are increased by sertraline in rats under oral glucose overload.
- R. Gomez, J. Huber, F. Lhullier, H. Barros
- Medicine, PsychologyBrazilian journal of medical and biological…
- 1 December 2001
It is demonstrated that sertraline increases glucose-stimulated insulin secretion without any change in peripheral insulin sensitivity.
Aldosterone Synthase Inhibition Improves Glucose Tolerance in Zucker Diabetic Fatty (ZDF) Rats.
- A. Hofmann, C. Brunssen, H. Morawietz
- Medicine, BiologyEndocrinology
- 15 August 2016
It is concluded that aldosterone synthase inhibition, in contrast to mineralocorticoid receptor antagonism, has the potential for beneficial effects on metabolic parameters in type 2 diabetes.
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