Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Silencing PinX1 compromises telomere length maintenance as well as tumorigenicity in telomerase-positive human cancer cells.
The nucleolar protein PinX1 has been proposed to be a putative tumor suppressor due to its binding to and inhibition of the catalytic activity of telomerase, an enzyme that is highly expressed in… Expand
Sports audio segmentation and classification
- J. Huang, Yuan Dong, J. Liu, Chengyu Dong, Haila Wang
- Computer Science
- IEEE International Conference on Network…
- 31 December 2009
TLDR
Cancer immunotherapy targeting the telomerase reverse transcriptase.
- Long Fei Huo, J. W. Tang, +4 authors M. C. Lin
- Biology, Medicine
- Cellular & molecular immunology
- 1 February 2006
The human telomerase reverse transcriptase (hTERT) is expressed in more than 85% of tumor cells but is usually not found in normal cells, which makes hTERT as an ideal tumor-associate antigen (TAA)… Expand
The new environment model building method of penetration mission based on the artificial potential field approach
- Y. Li, S. Hong, J. Huang, Song Mo
- Computer Science
- IEEE International Multi-Disciplinary Conference…
- 6 March 2012
TLDR
A novel glioblastoma cancer gene therapy using AAV-mediated long-term expression of human TERT C-terminal polypeptide
Glioblastoma multiforme is the most aggressive form of human brain tumor, which has no effective cure. Previously, we have demonstrated that overexpression of the C-terminal fragment of the human… Expand
Development of recombinant adeno-associated virus and adenovirus cocktail system for efficient hTERTC27 polypeptide-mediated cancer gene therapy
The low in vivo transduction efficiency of recombinant adeno-associated virus (rAAV) and the undesirably strong immunogenicity of adenovirus (rAdv) have limited their clinical utilization in cancer… Expand
Nucleolar localization of TERT is unrelated to telomerase function in human cells
Telomerase maintains telomere length and has been implicated in both aging and carcinogenesis of human cells. This enzyme is a specialized ribonucleoprotein (RNP) complex, minimally consisting of two… Expand
Ectopic expression of a COOH-terminal fragment of the human telomerase reverse transcriptase leads to telomere dysfunction and reduction of growth and tumorigenicity in HeLa cells.
The COOH-terminus of telomerase reverse transcriptase (hTERT) has been shown to participatein the nuclear translocation of TERT. Here, we constructed plasmids expressing the COOH-terminal M(r) 27,000… Expand
Mechanochemical mineralization of “very persistent” fluorocarbon surfactants ‒ 6:2 fluorotelomer sulfonate (6:2FTS) as an example
- Mengnan Lu, G. Cagnetta, K. Zhang, J. Huang, G. Yu
- Chemistry, Medicine
- Scientific Reports
- 7 December 2017
Fluorinated organic chemicals have a wide variety of industrial and consumer applications. For long time perfluorooctane sulfonate and perfluorooctanoic acid have been used as precursors for… Expand
Distributed group consensus for heterogeneous multi-agent systems
- J. Huang, Guoguang Wen, C. Wang, Zhi Chen
- Mathematics
- The 27th Chinese Control and Decision Conference…
- 23 May 2015
TLDR