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PPCA-Based Missing Data Imputation for Traffic Flow Volume: A Systematical Approach
  • Li Qu, J. Hu, Li Li, Y. Zhang
  • Mathematics, Computer Science
  • IEEE Transactions on Intelligent Transportation…
  • 1 September 2009
A new reliable method called probabilistic principal component analysis (PPCA) is put forward to impute the missing flow volume data based on historical data mining to reduce the root-mean-square imputation error by at least 25%. Expand
Formation of Hepatitis B Virus Covalently Closed Circular DNA: Removal of Genome-Linked Protein
The authors' results show that HBV CCC DNA formed in hepatoma cells was derived predominantly from RC DNA with a precise junction sequence, suggesting that the envelope protein(s) may negatively regulate a step in CCCDNA formation that precedes deproteination in both HBV and DHBV. Expand
Deamination-Independent Inhibition of Hepatitis B Virus Reverse Transcription by APOBEC3G
The inhibitory effect of APOBEC3 proteins on HBV replication was mainly at the DNA level, with only a minor effect on viral RNA packaging, and there was a preferential decrease in the accumulation of longer minus-strand DNA by A3G, compared to the shorter minus-Strand DNA. Expand
A hybrid forecasting approach applied to wind speed time series
In this paper, a hybrid forecasting approach, which combines the Ensemble Empirical Mode Decomposition (EEMD) and the Support Vector Machine (SVM), is proposed to improve the quality of wind speedExpand
Secretion of Genome-Free Hepatitis B Virus – Single Strand Blocking Model for Virion Morphogenesis of Para-retrovirus
It is found that the vast majority of HBV virions (over 90%) contained no DNA at all, indicating that NCs with no genome were enveloped and secreted as empty virions, and viral mutants bearing mutations precluding any DNA synthesis secreted exclusivelyempty virions. Expand
Hepatitis B virus–cell interactions and pathogenesis
This review will focus on the recent progress in understanding the virus–host interactions at the level of the infected cell, including the requirement of cellular chaperones for the initiation of HBV reverse transcription, and the role of the HBV X protein in modifying viral and cellular transcription and signaling. Expand
Photoacoustic ophthalmoscopy for in vivo retinal imaging
By integrating PAOM with SD-OCT, this work further achieved OCT-guided PAOM, which can provide multi-modal retinal imaging simultaneously, and demonstrated by imaging both the microanatomy and microvasculature of the rat retina in vivo. Expand
In Vitro Reconstitution of Functional Hepadnavirus Reverse Transcriptase with Cellular Chaperone Proteins
Five cellular chaperone proteins, all known cofactors of Hsp90, were sufficient to reconstitute a duck hepatitis B virus RT active in ε binding and protein priming in vitro, and this defined in vitro reconstitution system has paved the way for future biochemical and structural studies to elucidate the mechanisms of RT activation and chaperones functions. Expand
Reverse transcription-associated dephosphorylation of hepadnavirus nucleocapsids.
This work has devised a method to separate mature from immature duck hepatitis B virus NCs and has compared them to NCs derived from secreted virions, suggesting that the NC undergoes a dynamic change in phosphorylation state to fulfill its multiple roles at different stages of viral replication. Expand
Hepatitis B Virus Reverse Transcriptase and ε RNA Sequences Required for Specific Interaction In Vitro
The results suggest that recognition of some ε sequences by the RT may be required specifically for viral DNA synthesis and compared with those for in vivo pregenomic RNA (pgRNA) packaging clearly indicated that RT-ε interaction was necessary but not sufficient for pgRNA packaging. Expand