Oral immunotherapy for IgE‐mediated cow's milk allergy: a systematic review and meta‐analysis
- J. BrożekL. Terracciano H. Schünemann
- 1 March 2012
Medicine
A systematic review of randomized controlled trials and observational studies to assess the evidence supporting the use of oral immunotherapy in IgE‐mediated cow's milk allergy to inform the World Allergy Organization guidelines concluded that additional, larger RCTs measuring all patient‐important outcomes are still needed.
Antivirals for Treatment of Influenza
- Jonathan HsuN. Santesso H. Schünemann
- 3 April 2012
Medicine
Meta-analyses of the few studies providing effects with adjustment for confounders suggest that, in high-risk populations, oral oseltamivir may reduce mortality and pneumonia associated with influenza A and inhaled zanamivIR may provide a net benefit over no treatment of influenza.
Application of GRADE: Making evidence-based recommendations about diagnostic tests in clinical practice guidelines
- Jonathan HsuJ. Brożek Holger J. Schünemann
- 10 June 2011
Medicine
Implementation science : IS
A case study using the Grading of Recommendations Applicability, Development and Evaluation approach to develop a clinical practice guideline for the diagnosis of Cow Milk Allergy with the World Allergy Organization provides useful guidance for guideline developers and clinicians about what they ought to demand from clinical practice guidelines to facilitate implementation and strengthen confidence in recommendations about diagnostic tests.
S14– Using the GRADE approach to develop diagnostic guidelines in allergic disease
- A. SteinA. Fiocchi Enrico Compalat
- 1 July 2010
Medicine
Title: Application of Grade: Making Evidence-based Recommendations about Diagnostic Tests in Clinical Practice Guidelines
The authors describe a process and the approach to addressing various challenges faced when developing clinical practice guidelines on the use of diagnostic tools as well as how to expand on the concept of diagnostic testing.
Genetic Testing: Balancing Preventative Medicine with Privacy and Nondiscrimination
- Jonathan Hsu
- 2011
Law, Medicine
Antivirals for influenza: a summary of a systematic review and meta‐analysis of observational studies
- N. SantessoJonathan Hsu H. Schünemann
- 1 September 2013
Medicine
From observational studies of antiviral treatment for influenza, the summary estimates suggest that oseltamivir may reduce mortality, hospitalisation and duration of symptoms compared with no treatment, but patients may experience more complications compared withno treatment.