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Surgical treatment of craniopharyngiomas: experience with 168 patients.
OBJECT The goal of this study was to assess the outcome of surgical management in 168 consecutive patients harboring craniopharyngiomas treated between January 1983 and April 1997. METHODS In 148Expand
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Xanthogranuloma of the sellar region: a clinicopathological entity different from adamantinomatous craniopharyngioma
Abstract Xanthogranulomatous change of craniopharyngioma, consisting of cholesterol clefts, macrophages, chronic inflammatory infiltrates, necrotic debris and hemosiderin deposits, has beenExpand
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The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease.
CONTEXT We have recently reported somatic mutations in the ubiquitin-specific protease USP8 gene in a small series of adenomas of patients with Cushing's disease. OBJECTIVE To determine theExpand
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Diagnosis of Primary Hypophysitis in Germany.
CONTEXT Representative data on diagnostic findings in primary hypophysitis (PrHy) are scarce. OBJECTIVE The objective of the study was to collate consistent data on clinical features in a largeExpand
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SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary.
Gonadotroph pituitary adenomas (GPAs) often present as invasive macroadenomas not amenable to complete surgical resection. Radiotherapy is the only post-operative option for patients with largeExpand
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Surgical treatment of craniopharyngiomas: endocrinological results.
OBJECT This study aimed to elucidate the endocrinological outcome of craniopharyngioma surgery. In particular, endocrinological results were analyzed in relation to the surgical approach. The studyExpand
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Long-term remission and recurrence rates after first and second transsphenoidal surgery for Cushing's disease: care reality in the Munich Metropolitan Region.
OBJECTIVE Transsphenoidal surgery (TSS) presents the treatment of choice for Cushing's disease (CD). Remission and recurrence rates vary dependent on tumor size, extension, adenoma visibility onExpand
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Lymphocytic and granulomatous hypophysitis: experience with nine cases.
OBJECTIVE Lymphocytic hypophysitis and granulomatous hypophysitis are rarely encountered. The aim of this study was to demonstrate their clinical peculiarities among pituitary disorders and toExpand
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Long-term outcome in patients with acromegaly: analysis of 1344 patients from the German Acromegaly Register.
BACKGROUND Acromegaly is a rare disease with significant morbidity and increased mortality. Epidemiological data about therapeutic outcome under 'real life' conditions are scarce. OBJECTIVE ToExpand
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Expression of the growth hormone secretagogue receptor in pituitary adenomas and other neuroendocrine tumors.
Synthetic GH secretagogues (GHSs; GH-releasing peptides and their nonpeptide mimetics) stimulate GH release, activate the hypothalamo-pituitary-adrenal axis, and release PRL in vivo. Patients withExpand
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