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Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans.
TLDR
The results show that GLP-1 enhanced satiety and reduced energy intake and thus may play a physiological regulatory role in controlling appetite and energy intake in humans. Expand
The role of postprandial releases of insulin and incretin hormones in meal-induced satiety—effect of obesity and weight reduction
TLDR
Following weight reduction, GLP-1 response in the obese subjects apparently rose to a level between that of obese and lean subjects, and the data suggests that postprandial insulin and GIP responses are key players in short-term appetite regulation. Expand
Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men.
TLDR
It is demonstrated that GLP-1 decreases feelings of hunger and reduces energy intake in obese humans and one possible mechanism for this finding might be an increased satiety primarily mediated by gastric vagal afferent signals. Expand
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
TLDR
Near-normalisation of blood glucose for 4 weeks improves beta cell responsiveness to both GLP-1 and GIP by a factor of three to four, and no effect was found on betacell responsiveness to glucose alone. Expand
Resistant starch: the effect on postprandial glycemia, hormonal response, and satiety.
TLDR
Replacement of digestible starch with RS resulted in significant reductions in postprandial glycemia and insulinemia, and in the subjective sensations of satiety. Expand
The effect of physiological levels of glucagon-like peptide-1 on appetite, gastric emptying, energy and substrate metabolism in obesity
TLDR
It is concluded that GLP-1 in physiological concentrations powerfully reduces the rate of entry of nutrients into the circulation by a reduction of gastric emptying rate in obese subjects and may be beneficial in weight reduction. Expand
The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.
TLDR
The inhibitory effect of GLP-1 (7-36 amide) on acid secretion depends on intact vagal innervation of the stomach. Expand
Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man.
TLDR
GLP-1 and PYY are both potent inhibitors of the cephalic phase of acid secretion, indicating that at least part of the inhibitory effect of GLP-2 and PYY in man is mediated through neural pathways and seems to be independent of circulating concentrations of gastrin and somatostatin. Expand
Decreased postprandial thermogenesis and fat oxidation but increased fullness after a high-fiber meal compared with a low-fiber meal.
TLDR
A high-fiber meal decreased DIT and fat oxidation but increased fullness compared with a low- fiber meal, and fullness was increased and desire to eat decreased after the high-Fiber meal. Expand
Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink: a controlled trial
TLDR
Milk increased appetite scores and GLP-1 and GIP responses compared with SSSD, and there were no indications of ASSD increased appetite or EI compared with water. Expand
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