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The Addenbrooke's Cognitive Examination Revised (ACE‐R): a brief cognitive test battery for dementia screening
There is a clear need for brief, but sensitive and specific, cognitive screening instruments as evidenced by the popularity of the Addenbrooke's Cognitive Examination (ACE).
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia.
The revised criteria for behavioural variant frontotemporal dementia improve diagnostic accuracy compared with previously established criteria in a sample with known frontotmporal lobar degeneration and reflect the optimized diagnostic features, less restrictive exclusion features and a flexible structure that accommodates different initial clinical presentations. Expand
Structure and deterioration of semantic memory: a neuropsychological and computational investigation.
The authors present a parallel distributed processing implementation of this theory, in which semantic representations emerge from mechanisms that acquire the mappings between visual representations of objects and their verbal descriptions, to understand the structure of impaired performance in patients with selective and progressive impairments of conceptual knowledge. Expand
Theory of mind in patients with frontal variant frontotemporal dementia and Alzheimer's disease: theoretical and practical implications.
The hypothesis that patients with fvFTD, but not those with Alzheimer's disease, are impaired on tests of ToM is supported, and may explain some of the abnormalities in interpersonal behaviour that characterize fv FTD. Expand
Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia
A mutation in CHMP2B, encoding a component of the endosomal ESCRTIII complex, is identified and it is shown that it results in aberrant mRNA splicing in tissue samples from affected members of this family. Expand
A voxel‐based morphometry study of semantic dementia: Relationship between temporal lobe atrophy and semantic memory
It is confirmed that the anterior temporal lobe is critically involved in semantic processing, and dissociate its function from that of the adjacent frontal region. Expand
Validation of the Addenbrooke's Cognitive Examination III in Frontotemporal Dementia and Alzheimer's Disease
The results of this study provide objective validation of the Addenbrooke's Cognitive Examination (ACE-III) as a screening tool for cognitive deficits in FTD and AD. Expand
Memory, Amnesia and the Hippocampal System
This book fails to instantiate the clear, goal-directed, multi-disciplinary approach which it should be advocating in the rehabilitation process and gets little idea of what actually goes on in a team meeting or in therapy. Expand
A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia
The ACE is a brief and reliable bedside instrument for early detection of dementia, and offers a simple objective index to differentiate AD and FTD in mildly demented patients. Expand
Non-verbal semantic impairment in semantic dementia
Sound recognition and semantic association tasks are employed to investigate the nature of the verbal and non-verbal comprehension deficit in 10 patients with semantic dementia and support the notion that the patients' deficits across all modalities were due to degradation within a single, central network of conceptual knowledge. Expand