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Adenoviruses in the immunocompromised host
- J. Hierholzer
- Medicine, BiologyClinical Microbiology Reviews
- 1 July 1992
Treatments for adenovirus infections are of little proven value, although certain purine and pyrimidine analogs have shown beneficial effects in vitro and may be promising drugs.
Antigenic characterization of respiratory syncytial virus strains with monoclonal antibodies.
The results, along with those of previous studies, suggest that groups 1 and 3 are antigenically similar and group 2 is antigenically more distinct.
Percutaneous vertebroplasty proved to be a highly effective, minimal invasive interventional procedure to treat severely painful bone lesions of benign and malignant origin.
Detection of adenovirus in clinical specimens by polymerase chain reaction and liquid-phase hybridization quantitated by time-resolved fluorometry
- J. Hierholzer, P. Halonen, P. Dahlén, P. Bingham, M. McDonough
- Biology, MedicineJournal of clinical microbiology
- 1 July 1993
A liquid-phase hybridization system with biotin- and europium-labeled probes which are reacted after DNA amplification of a 161-bp region of the hexon gene and which are quantitated by time-resolved (TR) fluorometry in streptavidin-coated microtiter wells was shown to be advantageous as a quantitative measure of PCR products.
MRI and CT in the differential diagnosis of pleural disease.
When signal intensity and morphologic features are assessed, MRI is more useful and therefore superior to CT in differentiation of malignant from benign pleural disease.
Neutralization of respiratory syncytial virus by individual and mixtures of F and G protein monoclonal antibodies
The results suggest that interpretation of RSV neutralization with MAbs is complex and that studies of such neutralization should include mixtures of MAbs and multiple RSV strains.
Adenoviruses from Human Immunodeficiency Virus-Infected Individuals, Including Two Strains That Represent New Candidate Serotypes Ad50 and Ad51 of Species B1 and D, Respectively
- J. D. de Jong, A. G. Wermenbol, J. Hierholzer
- Biology, MedicineJournal of Clinical Microbiology
- 1 December 1999
Ad isolates from a large number of human immunodeficiency virus (HIV)-infected individuals were compared serologically and genetically with Ad isolate from immunocompetent patients, resulting in two new serotypes: candidate Ad serotype 50 ( prototype strain, Wan) of subspecies B1 and candidate AdSerotype 51 (prototype strain, Bom) of species D.
Adenoviruses from patients with AIDS: a plethora of serotypes and a description of five new serotypes of subgenus D (types 43-47).
- J. Hierholzer, R. Wigand, L. J. Anderson, T. Adrian, J. Gold
- Biology, MedicineThe Journal of infectious diseases
- 1 October 1988
The plethora of serotypes from patients with AIDS suggests that no epidemiological significance can be attached to any one serotype, and four intermediate types were related to the new serotypes.
Purification and biophysical properties of human coronavirus 229E
- J. Hierholzer
- 1 November 1976
Adult pneumonia in a general hospital. Etiology and host risk factors.
- R. J. Sullivan, W. Dowdle, W. Marine, J. Hierholzer
- Medicine, BiologyArchives of internal medicine
- 1 June 1972
Adult patients admitted to the medical service of a city-county hospital for treatment of presumptive acute pneumonia were followed up in a prospective study of pneumonia etiology from July 1, 1967, to June 30, 1968 and gram-negative bacilli or staphylococcal etiology were identified as mortality risk factors.