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The anti-inflammatory effect of glucocorticoids is mediated by glucocorticoid-induced leucine zipper in epithelial cells.
BACKGROUND Nuclear factor kappaB (NF-kappaB) plays a key role in the pathogenesis of asthma, being linked to the production of inflammatory cytokines that drive inflammation. A recently describedExpand
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Cigarette smoke decreases innate responses of epithelial cells to rhinovirus infection.
Exposure to cigarette smoke is associated with a significant increase in the risk for respiratory viral infections. The airway epithelium is the primary target for both cigarette smoke andExpand
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Detection of C1 inhibitor mutations in patients with hereditary angioedema.
BACKGROUND Hereditary angioedema (HAE) results from a deficiency in the functional level of C1 inhibitor caused by mutations in the C1 inhibitor gene. The mutations responsible for HAE have beenExpand
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Improved method for measuring C1rC1s‐(c1 inh)2 complexes by an enzyme‐linked immunosorbent assay
Measurement of C1rC1s‐(C1 inh)2 complexes in serum or plasma by enzyme‐linked immunosorbent assay (ELISA) has been proposed as a relatively convenient and sensitive means for assessing C1 activation.Expand
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Cold-dependent activation of complement: Recognition, assessment, and mechanism
AbstractCold-dependent activation of complement (CDAC) is a phenomenon characterized by low hemolytic complement activity in chilled serum. Complement component levels are normal when measuredExpand
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Improved method for measuring C1-r-C1-s-(C1 inh)2 complexes by an enzyme-linked immunosorbent assay.
Measurement of C1-r-C1-s-(C1 inh)2 complexes in serum or plasma by enzyme-linked immunosorbent assay (ELISA) has been proposed as a relatively convenient and sensitive means for assessing C1Expand