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Proteomic analysis of laser capture microdissected human prostate cancer and in vitro prostate cell lines
TLDR
The data demonstrate that 2‐D PAGE analysis of LCM‐derived cells can reliably detect alterations in protein expression associated with prostate cancer, and that these differentially expressed proteins are produced in high enough levels which could allow for their clinical utility as new targets for therapeutic intervention, serum markers, and/or imaging markers.
Loss of annexin 1 correlates with early onset of tumorigenesis in esophageal and prostate carcinoma.
Annexin I protein expression was evaluated in patient-matched longitudinal study sets of laser capture microdissected normal, premalignant, and invasive epithelium from human esophageal squamous cell
Treatment of muscle-invasive bladder cancer: progress and new challenges
TLDR
The critical issue in multimodal therapy for this very heterogeneous disease is individualized patient selection, and biologic-based staging and targeted therapies hold promise for the future.
Review Article VON RECKLINGHAUSEN'S DISEASE AND PHEOCHROMOCYTOMAS
TLDR
Pheochromocytomas occur in a small but defined number of patients with von Recklinghausen’s disease, and can be associated with significant morbidity and mortality if not detected.