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Biochemical verification of tobacco use and cessation.
Blood cannabinoids. I. Absorption of THC and formation of 11-OH-THC and THCCOOH during and after smoking marijuana.
This study provides the first complete pharmacokinetic profile of the absorption of THC and appearance of metabolites during marijuana smoking, which has implications for understanding the mechanisms underlying the performance-impairing effects of marijuana, as well as for aiding forensic interpretation of cannabinoid blood levels. Expand
The development of a cocaine craving questionnaire.
Examination of item content, correlations of factors across versions, and external correlates of the factors suggested that both versions of the questionnaire were represented by the same hierarchical factor structure. Expand
Higher levels of nicotine in arterial than in venous blood after cigarette smoking.
Differences between arterial and venous concentrations of nicotine in human subjects have implications for understanding the high degree of addictiveness and cardiovascular toxicity of smoked forms of drugs. Expand
Establishing a nicotine threshold for addiction. The implications for tobacco regulation.
On February 25, 1994, the Food and Drug Administration (FDA) released a letter to the Coalition on Smoking or Health announcing its intention to consider regulating cigarettes. The agency's premisesExpand
Nicotine and Smoking: A Review of Effects on Human Performance
Data from abstinent smokers support the conclusion that nicotine deprivation functions to maintain smoking in nicotine-dependent persons, in part, because nicotine can reverse withdrawal-induced deficits in several areas of performance. Expand
Nicotine delivery kinetics and abuse liability.
It is the case that initial tobacco use often escalates to compulsive use accompanied by tolerance and physical dependence, this is not usually observed with nicotine replacement therapies, and further research in developing alternative nicotine delivery forms may hold substantial promise in the treatment of tobacco dependence. Expand
Society for Research on Nicotine and Tobacco.
The research presented at the inaugural scientific meeting of the Society for Research on Nicotine and Tobacco demonstrated the vast diversity of areas of study involving nicotine and tobacco, as well as the rich opportunities for cross-communication among researchers from different disciplines. Expand
Pharmacotherapy for Nicotine Dependence 1
Combination therapies, long‐term medication therapies, and harm reduction strategies may further improve outcome with approved medications, and new medications such as varenicline and rimonabant are likely to reach tobacco users who are refractory to current treatments. Expand
Health risks associated with cigar smoking.
This article summarizes principal findings from a conference convened by the American Cancer Society in June 1998 to examine the health risks of cigar smoking, finding that rates of cigarsmoking are rising among both adults and adolescents. Expand