Biochemical verification of tobacco use and cessation.
- N. Benowitz, P. Jacob, W. Velicer
- MedicineNicotine & Tobacco Research
- 1 May 2002
Blood cannabinoids. I. Absorption of THC and formation of 11-OH-THC and THCCOOH during and after smoking marijuana.
- M. Huestis, J. Henningfield, E. Cone
- BiologyJournal of Analytical Toxicology
- 1 September 1992
This study provides the first complete pharmacokinetic profile of the absorption of THC and appearance of metabolites during marijuana smoking, which has implications for understanding the mechanisms underlying the performance-impairing effects of marijuana, as well as for aiding forensic interpretation of cannabinoid blood levels.
Higher levels of nicotine in arterial than in venous blood after cigarette smoking.
- J. Henningfield, J. Stapleton, N. Benowitz, R. Grayson, E. London
- MedicineDrug and Alcohol Dependence
- 1 June 1993
Establishing a nicotine threshold for addiction. The implications for tobacco regulation.
- N. Benowitz, J. Henningfield
- Medicine, Political ScienceNew England Journal of Medicine
- 14 July 1994
On February 25, 1994, the Food and Drug Administration (FDA) released a letter to the Coalition on Smoking or Health announcing its intention to consider regulating cigarettes. The agency's premises…
The development of a cocaine craving questionnaire.
- S. Tiffany, E. Singleton, C. Haertzen, J. Henningfield
- PsychologyDrug and Alcohol Dependence
- 1 December 1993
Nicotine delivery kinetics and abuse liability.
- J. Henningfield, R. Keenan
- Biology, PsychologyJournal of Consulting and Clinical Psychology
- 1 October 1993
It is the case that initial tobacco use often escalates to compulsive use accompanied by tolerance and physical dependence, this is not usually observed with nicotine replacement therapies, and further research in developing alternative nicotine delivery forms may hold substantial promise in the treatment of tobacco dependence.
Arterial and venous cocaine plasma concentrations in humans: relationship to route of administration, cardiovascular effects and subjective effects.
- S. Evans, E. Cone, J. Henningfield
- Biology, MedicineJournal of Pharmacology and Experimental…
- 1 December 1996
Even though arterial and venous cocaine concentrations were lower after smoked cocaine, compared with i.v. cocaine, the magnitudes of cardiovascular and subjective effects were similar, suggesting that smoked cocaine may produce a greater effect at similar concentrations.
Pharmacodynamic effects of new de-nicotinized cigarettes.
- W. Pickworth, R. Fant, R. Nelson, M. Rohrer, J. Henningfield
- Medicine, BiologyNicotine & Tobacco Research
- 1 December 1999
The de-nicotinized cigarettes may prove useful in evaluating effects of smoking independent of the delivery of nicotine, and extend previous research that suggested the process of smoking and components of tobacco smoke other than nicotine mediate some effects of cigarette smoking.
Nicotine and Smoking: A Review of Effects on Human Performance
- Stephen J. Heishma, Richard C. Taylor, J. Henningfield
- Psychology
- 1 November 1994
Data from abstinent smokers support the conclusion that nicotine deprivation functions to maintain smoking in nicotine-dependent persons, in part, because nicotine can reverse withdrawal-induced deficits in several areas of performance.
Pharmacotherapy for Nicotine Dependence 1
- J. Henningfield, R. Fant, A. Buchhalter, M. Stitzer
- MedicineCa
- 1 September 2005
Combination therapies, long‐term medication therapies, and harm reduction strategies may further improve outcome with approved medications, and new medications such as varenicline and rimonabant are likely to reach tobacco users who are refractory to current treatments.
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