The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs.
Synthesis, cytotoxicity, and antioxidative activity of minor prenylated chalcones from Humulus lupulus.
The minor hop ( Humulus lupulus) chalcones 3'-geranylchalconaringenin (3), 5'-prenylxanthohumol (4), flavokawin (5), xanthohumol H (8), xanthohumol C (9), and 1'',2''-dihydroxanthohumol C (10) were…
Novel extracellular diterpenoids with biological activity from the cyanobacterium Nostoc commune.
- B. Jaki, J. Orjala, J. Heilmann, A. Linden, B. Vogler, O. Sticher
- ChemistryJournal of Natural Products
- 1 March 2000
Five novel extracellular metabolites with an unprecedented diterpenoid skeleton, comnostins A-E, isolated from the culture medium of the terrestrial cyanobacterium Nostoc commune by means of bioguided isolation showed antibacterial activities.
Further phenols and polyacetylenes from the rhizomes of Atractylodes lancea and their anti-inflammatory activity.
The fatty acids linoleic acid, oleic acid and palmitic acid with previously established 5-LOX-/COX-1 inhibitory actions were identified as major constituents of the n-hexane extract and thus seem to contribute to the plant's in vitro activity.
Biological Screening of Terrestrial and Freshwater Cyanobacteria for Antimicrobial Activity, Brine Shrimp Lethality, and Cytotoxicity
The results prove that terrestrial and freshwater cyanobacteria are still a promising source of new bioactive natural products.
Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells.
- C. Dorn, T. Weiss, J. Heilmann, C. Hellerbrand
- Biology, MedicineInternational Journal of Oncology
- 27 December 2009
It is shown that xanthohumol can ameliorate different pro-tumorigenic mechanisms known to promote HCC progression, indicating its potential as promising therapeutic agent that selectively affects cancer cells.
Tea catechins' affinity for human cannabinoid receptors.
New cytotoxic 6,7-cis and 6,7-trans configured guaianolides from Warionia saharae.
Using cytotoxicity against the KB cancer cell line (ATCC CCL17) as a lead, bioactivity-guided fractionation of the MeOH-soluble part of the DCM extract of Warionia saharae leaves led to the isolation…
Natural and non-natural prenylated chalcones: synthesis, cytotoxicity and anti-oxidative activity.
Synthesis, cytotoxicity, anti-oxidative and anti-inflammatory activity of chalcones and influence of A-ring modifications on the pharmacological effect.