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The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs.
The ethanol extract itself or single constituents of F. parviflora could be a promising alternative source of anthelmintic for the treatment of gastrointestinal trichostrongylids in small ruminants. Expand
Novel extracellular diterpenoids with biological activity from the cyanobacterium Nostoc commune.
Five novel extracellular metabolites with an unprecedented diterpenoid skeleton, comnostins A-E, isolated from the culture medium of the terrestrial cyanobacterium Nostoc commune by means of bioguided isolation showed antibacterial activities. Expand
Natural and non-natural prenylated chalcones: synthesis, cytotoxicity and anti-oxidative activity.
A general strategy for the synthesis of 3'-prenylated chalcones was established and a series of prenylated hydroxychalcones, including the hop secondary metabolites xanthohumol, revealed interesting synthetic possibilities for the development of more potent compounds. Expand
Synthesis, cytotoxicity, and antioxidative activity of minor prenylated chalcones from Humulus lupulus.
The minor hop ( Humulus lupulus) chalcones 3'-geranylchalconaringenin (3), 5'-prenylxanthohumol (4), flavokawin (5), xanthohumol H (8), xanthohumol C (9), and 1'',2''-dihydroxanthohumol C (10) wereExpand
Further phenols and polyacetylenes from the rhizomes of Atractylodes lancea and their anti-inflammatory activity.
The fatty acids linoleic acid, oleic acid and palmitic acid with previously established 5-LOX-/COX-1 inhibitory actions were identified as major constituents of the n-hexane extract and thus seem to contribute to the plant's in vitro activity. Expand
Oxidation products of abietic acid and its methyl ester.
The cytotoxicity of several compounds against KB cells was evaluated, and weak activity was observed for 6, 7, and 8 with IC(50) values of 12.5, 4.8 microg/mL, respectively. Expand
Biological Screening of Terrestrial and Freshwater Cyanobacteria for Antimicrobial Activity, Brine Shrimp Lethality, and Cytotoxicity
The results prove that terrestrial and freshwater cyanobacteria are still a promising source of new bioactive natural products. Expand
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
While connecting beta-carboline units by alkylene spacers in two different series of compounds and subsequent evaluation of their AChE/BChE-inhibitory potential, it was found that several of these bivalent beta-carbolines were potent NR blockers. Expand
Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells.
The data showed that xanthohumol can ameliorate different pro-tumorigenic mechanisms known to promote HCC progression, indicating its potential as promising therapeutic agent that selectively affects cancer cells. Expand
Transport of alkamides from Echinacea species through Caco-2 monolayers.
The assumption that the alkamides can be easily transported from the intestinum and hence may contribute to the in vivo effects of Echinacea preparations is supported. Expand