J. Heath

Publications412
h-index91
Citations46,628
Highly Influential Citations488
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C60: Buckminsterfullerene
During experiments aimed at understanding the mechanisms by which long-chain carbon molecules are formed in interstellar space and circumstellar shells1, graphite has been vaporized by laser…
Systems Biology and New Technologies Enable Predictive and Preventative Medicine
Systems approaches to disease are grounded in the idea that disease-perturbed protein and gene regulatory networks differ from their normal counterparts; we have been pursuing the possibility that…
Silicon nanowires as efficient thermoelectric materials
TLDR
Independent measurements of the Seebeck coefficient, the electrical conductivity and the thermal conductivity, combined with theory, indicate that the improved efficiency originates from phonon effects, and these results are expected to apply to other classes of semiconductor nanomaterials.
A Defect-Tolerant Computer Architecture: Opportunities for Nanotechnology
TLDR
The defect-tolerant architecture of Teramac, which incorporates a high communication bandwith that enables it to easily route around defects, has significant implications for any future nanometer-scale computational paradigm.
Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis.
Silicon Nanowires as Efficient Thermoelectric Materials.
Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA
TLDR
Single-cell analyses of patient-derived models and clinical samples from glioblastoma patients treated with EGFR tyrosine kinase inhibitors demonstrate that tumor cells reversibly up-regulate or suppress mutant EGFR expression, conferring distinct cellular phenotypes to reach an optimal equilibrium for growth.
A 160-kilobit molecular electronic memory patterned at 1011 bits per square centimetre
TLDR
A 160,000-bit molecular electronic memory circuit, fabricated at a density of 1011 bits cm-2 (pitch 33 nm; memory cell size 0.0011 μm2), that is, roughly analogous to the dimensions of a DRAM circuit projected to be available by 2020.
Quantitative real-time measurements of DNA hybridization with alkylated nonoxidized silicon nanowires in electrolyte solution.
TLDR
It is demonstrated that SiNWs can be utilized to quantitate the solution-phase concentration of biomolecules at low concentrations, and the importance of surface chemistry for optimizing biomolecular sensing with silicon nanowires is demonstrated.
Highly ordered nanowire arrays on plastic substrates for ultrasensitive flexible chemical sensors.
TLDR
This work presents a scalable and parallel process for transferring hundreds of pre-aligned silicon nanowires onto plastic to yield highly ordered films for low-power sensor chips, and uses SiO2 surface chemistries to construct a 'nano-electronic nose' library.
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