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11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study)
Although the proportional use of second-generation antipsychotic drugs rose from 13% to 64% during follow-up, the gap in life expectancy between patients with schizophrenia and the general population did not widen between 1996 and 2006. Expand
A nationwide cohort study of oral and depot antipsychotics after first hospitalization for schizophrenia.
Use of depot antipsychotics was associated with a significantly lower risk of rehospitalization than use of oral formulations of the same compounds, and clozapine and olanzapine were associated with more favorable outcomes. Expand
Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects.
This study provides further evidence for the hypothesis that the DISC1 gene is involved in the aetiology of schizophrenia, and implies a putative sex difference for the effect of the gene. Expand
Completed suicide after a suicide attempt: a 37-year follow-up study.
A history of a suicide attempt by self-poisoning indicates suicide risk over the entire adult lifetime, and suicides continued to accumulate almost four decades after the index suicide attempt. Expand
Meta‐analysis of observational studies of serum 25‐hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma
A consistent inverse relationship between serum 25‐hydroxyvitamin D levels and colorectal cancer was found and differences between cases and controls in the season of blood draw or in overweight/obesity or physical inactivity could not explain the results. Expand
Nocturia frequency, bother, and quality of life: how often is too often? A population-based study in Finland.
At least two voids per night is associated with impaired HRQoL, and one void per night does not identify subjects with interference from nocturia and, thus, is not a suitable criterion for clinically relevantNocturia. Expand
Is low dietary intake of omega-3 fatty acids associated with depression?
Dietary intake of omega-3 fatty acids showed no association with low mood level and there were no associations with major depressive episodes, suicide, or suicide in Finland. Expand
Finnish health and social welfare registers in epidemiological research
Finland introduced a personal identification number system in 1964, and since then practically all administrative registers have included this unique identification code. Currently Finland has strictExpand
Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder: observational follow-up
Patients treated with perphenazine depot, clozapine, or olanzapine have a substantially lower risk of rehospitalisation or discontinuation of their initial treatment than do patients treated with haloperidol, and the effectiveness of first and second generation antipsychotics varies greatly in the community. Expand
High concordance of bipolar I disorder in a nationwide sample of twins.
The high heritability of bipolar disorder was demonstrated in a nationwide population-based twin sample assessed with structured personal interviews, in which the diagnoses were made by using structured, personal interviews. Expand