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Relation between phylogeny of African green monkey CD4 genes and their respective simian immunodeficiency virus genes
Abstract: An apparent species‐specific relatedness of SIVagm suggests a coevolution with their natural hosts. However, the exact species or subspecies classification of African green monkeys, AGM, isExpand
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Mutations in CCR5-coding sequences are not associated with SIV carrier status in African nonhuman primates.
African monkeys can be naturally infected with SIV but do not progress to AIDS. Since mutations in the human CCR5 gene have been shown to influence susceptibility to HIV infection and diseaseExpand
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Receptor function of CD4 structures from African green monkey and pig-tail macaque for simian immunodeficiency virus, SIVsm, SIVagm, and human immunodeficiency virus type-1.
Differences in kinetics of infection, cellular tropism, and cytopathology of SIV and HIV appear to depend on both viral and host factors. We investigated the role of critical CD4 structures fromExpand
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Identification of three N-linked glycans in the V4–V5 region of HIV-1 gp 120, dispensable for CD4-binding and fusion activity of gp 120
SummarySite-directed mutagenesis was used to study the biological significance of three N-linked glycans (linked to Asn 406, Asn 448, and Asn 463), situated in the CD4-binding region of gp120.Expand
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A Novel Protein Tag from Herpes Simplex Virus Type 1 DNA Polymerase
An epitope (HPOL) derived from the so-called thumb region of the herpes simplex virus type 1 DNA polymerase in combination with a monoclonal antibody (MAb 1051c) was tested for protein tagging. UsingExpand
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