J. Haldar

Publications43
h-index20
Citations1,619
Highly Influential Citations22
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[1-beta-Mercapto-beta,beta-cyclopentamethylenepropionic acid),2-(O-methyl)tyrosine ]argine-vasopressin and [1-beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)]argine-vasopressine, two…
  • 416
  • 7
Solid-phase synthesis of 16 potent (selective and nonselective) in vivo antagonists of oxytocin.
We describe the synthesis and some pharmacological properties of 16 new in vivo antagonists of oxytocin. These are based on modifications of three peptides: A, B, and C. A is our previously reported… Expand
  • 97
  • 4
Design and synthesis of potent in vivo antagonists of oxytocin.
We have previously shown that the substitution of 8-ornithine and 2-O-methyltyrosine alone and in combination in [1-deaminopenicillamine] oxytocin (dPOT) brought about enhancements in antagonistic… Expand
  • 109
  • 2
Synthesis and some pharmacological properties of [4-threonine, 7-glycine]oxytocin, [1-(L-2-hydroxy-3-mercaptopropanoic acid), 4-threonine, 7-glycine]oxytocin (hydroxy[Thr4, Gly7]oxytocin), and…
[4-Threonine, 7-glycine]oxytocin and [1-(L-2-hydroxy-3-mercaptopropanoic acid), 4-threonine, 7-glycine]oxytocin (hydroxy[Thr4, Gly7]oxytocin) were synthesized by a combination of solid-phase and… Expand
  • 84
  • 2
Independent release of oxytocin and vasopressin during parturition in the rabbit
  • J. Haldar
  • Medicine
  • The Journal of physiology
  • 1 March 1970
1. Oxytocin and vasopressin were assayed in samples of blood collected from seven conscious rabbits during parturition.
  • 32
  • 2
Design of potent antagonists of the vasopressor response to arginine-vasopressin.
As part of a program in which we are attempting to design and synthesize antagonists of the vasopressor response to arginine-vasopressin (AVP), [1-deaminopenicillamine]arginine-vasopressin (dPAVP),… Expand
  • 79
  • 1
[1-(beta-mercapto-beta,beta-cyclopentamethylenepropionic acid),4-valine,-8-D-arginine]vasopressin, a potent and selective inhibitor of the vasopressor response to arginine-vasopressin.
As part of a program in which we are attempting the design and synthesis of an antagonist of the antidiuretic response to arginine-vasopressin (AVP)… Expand
  • 40
  • 1
The design of effective in vivo antagonists of rat uterus and milk ejection responses to oxytocin.
Several new synthetic analogs of the oxytocin antagonist [1-deaminopenicillamine]oxytocin have been prepared and tested for their abilities to inhibit responses to oxytocin by the isolated rat uterus… Expand
  • 40
  • 1
Blood levels of oxytocin and vasopressin during suckling in the rabbit and the problem of their independent release
1. Oxytocin and vasopressin were assayed in samples of blood collected from conscious rabbits during suckling. The milk yields were determined from the weight gain of the litters.
  • 39
  • 1
Hypothalamic oxytocin
Immunocytochemical studies in normal rats show an association between oxytocin (OT) neurons and cerebral blood vessels. This is supported by the finding of neurophysin (NP) immunoreactivity in blood… Expand
  • 14
  • 1