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The interaction of phospholipase A2 with phospholipid analogues and inhibitors.
TLDR
This systematic study of phospholipid-phospholipase A2 inhibition led to the following conclusions about sn-2 amide analogues, presumably because the amide forms a hydrogen bond with the water molecule in the enzyme active site, stabilizing its binding. Expand
Samurai In The Surf: The Arrival Of The Japanese On The Gold Coast In The 1980s
Samurai in the Surf explores the history of Japanese investment in the 1980s, following a money-trail that leads back to a ballooning Japanese economy and a colorful array of investment sources. TheExpand
Synthesis of Phosphatidylcholine Analogues Derived from Glyceric Acid: a New Class of Biologically Active Phospholipid Compounds.
Synthesis of a new class of phosphatidylcholine analogues derived from glyceric acid is reported for spectroscopic studies of phospholipases and conformation of phospholipid side-chains in biologicalExpand
Cytotoxicity of platelet activating factor and related alkyl-phospholipid analogs in human leukemia cells, polymorphonuclear neutrophils, and skin fibroblasts.
TLDR
The kinetic events of the cellular responses in both normal and HL-60 cells in relation to the antineoplastic activities of unnatural ether-linked phospholipid analogs that are structurally related to L-PAF are characterized. Expand
The Gold Coast, Australia: Spatial model of its development and the impact of the cycle of foreign investment in property during the late 1980's
Zusammenfassung: Gold Coast, Australien: ein raumliches Entwicklungsmodell und der Einflufi auslandischer Investi tionen im Immobiliensektor wahrend der spaten achtziger Jahre Die Gold Coast an derExpand
Inhibition of protein kinase C, (sodium plus potassium)-activated adenosine triphosphatase, and sodium pump by synthetic phospholipid analogues.
TLDR
It is suggested that Na,K-ATPase (sodium pump) might represent a hitherto unrecognized site of action for the lipid analogues, and that the antineoplastic effects of the agents might be due to, in part, inhibition of both protein kinase C and Na, K- ATPase and perhaps other membrane-associated enzymes. Expand
Cytotoxicity of platelet activating factor and related alkyl- phospholipid analogs in human leukemia cells, polymorphonuclear neutrophils, and skin fibroblasts
TLDR
The kinetic events of the cellular responses in both normal and HL-60 cells in relation to the antineoplastic activities of unnatural ether-linked phospholipid analogs that are structurally related to L-PAF are characterized. Expand
Structural features of platelet activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) required for hypotensive and platelet serotonin responses.
  • M. Blank, E. Cress, +5 authors F. Snyder
  • Chemistry, Medicine
  • Research communications in chemical pathology and…
  • 1 October 1982
A number of analogs similar in structure to biologically active 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet activating factor) were tested for their relative effectiveness in lowering theExpand
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